Lixisenatide

Modify Date: 2024-01-02 16:03:28

Lixisenatide Structure
Lixisenatide structure
Common Name Lixisenatide
CAS Number 320367-13-3 Molecular Weight 4858.49000
Density N/A Boiling Point N/A
Molecular Formula C215H347N61O65S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Lixisenatide


Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM). Sequence: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Ser-Lys-Lys-Lys-Lys-Lys-Lys-NH2.

 Names

Name lixisenatide
Synonym More Synonyms

 Lixisenatide Biological Activity

Description Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist that can be used in the treatment of type 2 diabetes mellitus (T2DM). Sequence: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Ser-Lys-Lys-Lys-Lys-Lys-Lys-NH2.
Related Catalog
Target

GLP-1 receptor[1][2].

References

[1]. Ahrén B et al. Postprandial Glucagon Reductions Correlate to Reductions in Postprandial Glucose and Glycated Hemoglobin with Lixisenatide Treatment in Type 2 Diabetes Mellitus: A Post Hoc Analysis. Diabetes Ther. 2016 Jun 18

[2]. Lorenz M, et al. Effects of lixisenatide once daily on gastric emptying in type 2 diabetes--relationship to postprandial glycemia. Regul Pept. 2013 Aug 10;185:1-8.

 Chemical & Physical Properties

Molecular Formula C215H347N61O65S
Molecular Weight 4858.49000
Exact Mass 4855.54000
PSA 2085.46000
LogP 2.13170
Storage condition -20°C

 Synonyms

ZP 10
AVE 0010
ZP10A peptide
lixisenatide
des-38-proline-exendine-4 (Heloderma suspectum)-(1-39)- peptidylpenta-L-lysyl-L-lysinamide
AVE0010
Lyxumia
UNII-74O62BB01U
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