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79350-37-1

79350-37-1 structure
79350-37-1 structure
  • Name: Cefixime
  • Chemical Name: cefixime
  • CAS Number: 79350-37-1
  • Molecular Formula: C16H15N5O7S2
  • Molecular Weight: 453.450
  • Catalog: API Antibiotics Cephalosporin
  • Create Date: 2018-08-02 16:47:07
  • Modify Date: 2026-07-01 16:42:40
  • Cefixime is an antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections.
Name cefixime
Synonyms Cefixime double chain Impurity
Cefspan
Cefixime 13C 15N2Q: What is Cefixime 13C 15N2 Q: What is the CAS Number of Cefixime 13C 15N2 Q: What is the storage condition of Cefixime 13C 15N2 Q: What e the applications of Cefixime 13C 15N2
Cefixime Trihydrate (Micronized)
CEFIXIME TRIHYDRATE
(6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-[(cboxymethoxy)imino]acetamido]-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic Acid
[6R-[6α，7β(Z)]]-7-[[(2-Amino-4-thiazolyl)[(cboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid
CEFIXIME CHALOSPORINS
Ceftmral
Supracef
Saprax
Choral
8-[[2-(2-Amino-1,3-thiazol-4-yl)-2-(cboxymethoxyimino)acetyl]amino]-4-ethenyl-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-cboxylic acid trihydrate
CEFIXME TRIHYDRATE
Cefixime CRS
(6R,6β)-7α-[[(2-Amino-4-thiazolyl)[(Z)-(cboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid
MFCD03788802
YTTERBIUM(III) IONOPHORE I
7-[[2-(2-amino-4-thiazolyl)-2-(cboxymethoxyimino)-1-oxoethyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid trihydrate
8-[[2-(2-amino-1,3-thiazol-4-yl)-2-(cboxymethoxyimino)acetyl]amino]-4-ethenyl-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-cboxylic acid
Cefixime Monomer
CEFIXIME MICRONIZED
CEFIXIME(7-[[(2-AMINO-4-THIAZOLGL)(CBOXYMETHOXG)IMINO]ACETYL]AMINO-3-VINYL-8-OXO-5-THIA-1-AZABICYCLO[4,2,0]OCT-2-ENE-2-CBOXYLICACIDTRIHYDRATE)
)(cboxymethoxy)imino)acetylamino)-3-ethenyl-8-oxo-,(6r-(6-alpha,7-beta(z)))
Antibiotic FK-027
Unixime
Oroken
CEFIXIME (NON-STERILE DRUG SUBSTANCE)
(6R,7R)-7-({(2-Amino-1,3-thiazol-4-yl)[(carboxymethoxy)imino]acetyl}amino)-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)[(cboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-, (6R,7R)- (9CI)
Cefixime //BP
(6R,7R)-7-[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-[(cboxyMethoxy)iMino]acetaMido]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid
CFIX
Cefixime Impurity D (cefixime (E)-isomer)
fr17027
Cefixime in methanol
(6R,7R)-7-[2-(2-AMINO-4-THIAZOLYL)GLOXYLAMIDO]-8-OXO-3-VINYL-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CBOXYLIC ACID, 72-(Z)-[O-(CBOXYMETHYL)OXIME]TRIHYDRATE
Cefixoral
Cexime
Cefixime (comp)
(6R,7R)-7-((Z)-2-(2-Aminothiazol-4-yl)-2-((cboxymethoxy)imino)acetamido)-8-oxo-3-vinyl-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylicacid
fk027
Cefixim
CefiximeQ: What is Cefixime Q: What is the CAS Number of Cefixime
AcetazolaMide IMpurity C
cl284635
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-[(cboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-, (6R,7R)
Cefixime, 10 mM in DMSO
(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-[(cboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic Acid
CEFIXIME
(6R,7R)-7-[[(Z)-(2-Amino-4-thiazolyl)[(cboxymethoxy)imino]acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid
Cefixime Cefspan Oroken
(6R,7R)-7-({(2Z)-2-(2-AMINO-1,3-THIAZOL-4-YL)-2-[(CBOXYMETHOXY)IMINO]ACETYL}AMINO)-8-OXO-3-VINYL-5-THIA-1-AZABICYCLO[4.2.0]OCT-2-ENE-2-CBOXYLIC ACID
Cefiximum
Suprax
Cefixime Δ3 isomer impurity
Description Cefixime is an antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections.
Related Catalog
Density 1.9±0.1 g/cm3
Melting Point 218-225°C
Molecular Formula C16H15N5O7S2
Molecular Weight 453.450
Exact Mass 453.041290
PSA 238.05000
LogP 1.00
Index of Refraction 1.811
Storage condition Hygroscopic, Refrigerator, Under Inert Atmosphere
Water Solubility 55.11 mg/L

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XI0367200
CHEMICAL NAME :
5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((2-amino-4-thiazolyl) (carboxymethoxy)imino)acetylamino)-3-ethenyl-8-oxo-, (6R-(6-alpha,7-beta(Z)))-
CAS REGISTRY NUMBER :
79350-37-1
LAST UPDATED :
199612
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C16-H15-N5-O7-S2
MOLECULAR WEIGHT :
453.48

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 20,3509,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 20,3509,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
6990 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 20,3509,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 20,3509,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity)
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 20,3509,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
4420 mg/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 20,3509,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>600 mg/kg
TOXIC EFFECTS :
Gastrointestinal - hypermotility, diarrhea
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 20,3509,1986
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
>3200 mg/kg
TOXIC EFFECTS :
Gastrointestinal - nausea or vomiting Kidney, Ureter, Bladder - structural or functional changes in ureter Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 20,3509,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
371 gm/kg/53W-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - other changes Endocrine - other changes Related to Chronic Data - death
REFERENCE :
KSRNAM Kiso to Rinsho. Clinical Report. (Yubunsha Co., Ltd., 1-5, Kanda Suda-Cho, Chiyoda-ku, KS Bldg., Tokyo 101, Japan) V.1- 1960- Volume(issue)/page/year: 20,3509,1986
Hazard Codes Xn: Harmful;
Risk Phrases R42/43
Safety Phrases S22-S36/37-S45
WGK Germany 3
HS Code 2941905990
88621-01-6 structure

88621-01-6

~%

79350-37-1 structure

79350-37-1

Literature: WO2006/67806 A1, ; Page/Page column 9-10 ;
HS Code 2941905990
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