Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Clorgyline hydrochloride
Price: ￥448.0/25mg ￥5428.0/500mg ￥1358.0/100mg
Purity: 98.0%
Stocking Period: 2 Day
Contact: Liu jia

DC Chemicals Limited
China
Product Name: Clorgyline HCl
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: CLORGYLINE HYDROCHLORIDE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

17780-75-5

17780-75-5 structure

Name: Clorgyline hydrochloride
Chemical Name: 3-(2,4-dichlorophenoxy)-N-methyl-N-prop-2-ynylpropan-1-amine,hydrochloride
CAS Number: 17780-75-5
Molecular Formula: C₁₃H₁₆Cl₃NO
Molecular Weight: 308.631
Catalog: Signaling Pathways Neuronal Signaling Monoamine Oxidase
Create Date: 2018-12-27 18:48:11
Modify Date: 2024-01-09 15:18:45
Clorgyline hydrochloride is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A) that is used in scientific research; structurally related to Pargyline.

Name	3-(2,4-dichlorophenoxy)-N-methyl-N-prop-2-ynylpropan-1-amine,hydrochloride
Synonyms	N-Methyl-N-propargyl-3-(2,4-dichlorophenoxy)propylamine hydrochloride 2-Propyn-1-amine, N-(3-(2,4-dichlorophenoxy)propyl)-N-methyl-, hydrochloride (9CI) CLORGYLINE HYDROCHLORIDE Clorgyline HCl N-[3-(2,4-Dichlorophenoxy)propyl]-N-methylprop-2-yn-1-amine hydrochloride (1:1) B 9302 2-Propyn-1-amine, N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-, hydrochloride (1:1) EINECS 241-760-5 N-[3-(2,4-Dichlorophenoxy)propyl]-N-methyl-2-propyn-1-amine hydrochloride (1:1) clorgiline hydrochloride N-[3-(2,4-dichlorophenoxy)propyl]-N-methyl-2-propynylamine hydrochloride Clorgiline (hydrochloride)

Description	Clorgyline hydrochloride is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A) that is used in scientific research; structurally related to Pargyline.
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Metabolic Disease
References	[1]. Murphy DL, et al. Differential trace amine alterations in individuals receiving acetylenic inhibitors of MAO-A (clorgyline) or MAO-B (selegiline and pargyline). Journal of neural transmission. Supplementum 52: 39-48.

Boiling Point	361.3ºC at 760mmHg
Molecular Formula	C₁₃H₁₆Cl₃NO
Molecular Weight	308.631
Flash Point	172.3ºC
Exact Mass	307.029755
PSA	12.47000
LogP	4.12930
Vapour Pressure	2.1E-05mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UI0675000

CHEMICAL NAME :: Propylamine, 3-(2,4-dichlorophenoxy)-N-methyl-N-propargyl-, hydrochloride

CAS REGISTRY NUMBER :: 17780-75-5

LAST UPDATED :: 199509

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C13-H15-Cl2-N-O.Cl-H

MOLECULAR WEIGHT :: 308.65

WISWESSER LINE NOTATION :: GR CG DO3N1&2UU1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 210 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 17,1285,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 62 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 17,1285,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 430 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 17,1285,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 350 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 21,56,1978

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 17,1285,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 94 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 17,1285,1968

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H301-H312-H332
Precautionary Statements	P280-P301 + P310
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	20/21/22
RIDADR	UN 2811 6.1/PG 3
RTECS	UI0675000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2922299090

HS Code	2922299090
Summary	2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

17780-75-5	1406-14-0
6138-79-0	127228-87-9
143851-98-3	929-73-7
65546-09-0	1135280-78-2
56-99-5	1406-02-6