1477-50-5

1477-50-5 structure

Name: Indole-2-carboxylic acid
Chemical Name: Indole-2-carboxylic acid
CAS Number: 1477-50-5
Molecular Formula: C₉H₇NO₂
Molecular Weight: 161.157
Catalog: Signaling Pathways Membrane Transporter/Ion Channel iGluR
Create Date: 2018-06-19 18:12:07
Modify Date: 2025-08-22 13:01:17
Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current[1][2].

Name	Indole-2-carboxylic acid
Synonyms	1H-Indole-2-carboxylic acid T56 BMJ CVQ Indole-2-carboxylic acid 2-Carboxyindole 2-Indolecarboxylic acid MFCD00005611 EINECS 216-030-4

Description	Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current[1][2].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> iGluR Research Areas >> Neurological Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> iGluR
Target	Human Endogenous Metabolite
References	[1]. 2-Indolecarboxylic acid. [2]. J E Huettner, et al. Indole-2-carboxylic Acid: A Competitive Antagonist of Potentiation by Glycine at the NMDA Receptor. Science. 1989 Mar 24;243(4898):1611-3.

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	Xi: Irritant;Xn: Harmful;
Risk Phrases	R36/37/38
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	NK7882812
HS Code	29339990

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%