CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
KI0950000
-
CHEMICAL NAME :
-
Ethane, 1,2-dichloro-1,1-difluoro-
-
CAS REGISTRY NUMBER :
-
1649-08-7
-
BEILSTEIN REFERENCE NO. :
-
1733206
-
LAST UPDATED :
-
199712
-
DATA ITEMS CITED :
-
9
-
MOLECULAR FORMULA :
-
C2-H2-Cl2-F2
-
MOLECULAR WEIGHT :
-
134.94
-
WISWESSER LINE NOTATION :
-
GXFF1G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
Standard Draize test
-
ROUTE OF EXPOSURE :
-
Administration into the eye
-
SPECIES OBSERVED :
-
Rodent - rabbit
-
REFERENCE :
-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0530580 ** ACUTE TOXICITY DATA **
-
TYPE OF TEST :
-
LDLo - Lowest published lethal dose
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
25 gm/kg
-
TOXIC EFFECTS :
-
Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - respiratory depression
-
REFERENCE :
-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0530581
-
TYPE OF TEST :
-
LCLo - Lowest published lethal concentration
-
ROUTE OF EXPOSURE :
-
Inhalation
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
20000 ppm/4H
-
TOXIC EFFECTS :
-
Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Liver - other changes
-
REFERENCE :
-
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 19,1,1971 ** OTHER MULTIPLE DOSE TOXICITY DATA **
-
TYPE OF TEST :
-
TCLo - Lowest published toxic concentration
-
ROUTE OF EXPOSURE :
-
Inhalation
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
2000 ppm/6H/13W-I
-
TOXIC EFFECTS :
-
Liver - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
-
REFERENCE :
-
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0530614 ** REPRODUCTIVE DATA **
-
TYPE OF TEST :
-
TCLo - Lowest published toxic concentration
-
ROUTE OF EXPOSURE :
-
Inhalation
-
DOSE :
-
2000 ppm/6H
-
SEX/DURATION :
-
male 14 week(s) pre-mating
-
TOXIC EFFECTS :
-
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)
-
REFERENCE :
-
EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0587-0676
|
