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6009-98-9

6009-98-9 structure
6009-98-9 structure
  • Name: Taurochenodeoxycholic acid sodium salt
  • Chemical Name: Sodium taurochenodeoxycholate
  • CAS Number: 6009-98-9
  • Molecular Formula: C26H44NNaO6S
  • Molecular Weight: 521.685
  • Catalog: Signaling Pathways Apoptosis Apoptosis
  • Create Date: 2018-09-01 17:44:58
  • Modify Date: 2026-06-30 11:58:12
  • Taurochenodeoxycholic acid sodium salt (12-Deoxycholyltaurine sodium salt) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties[1][2].
Name Sodium taurochenodeoxycholate
Synonyms Aurochenodeoxycholic acid sodiuM salt
3α,7α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt
Taurochenodeoxycholic Acid Sodium Salt in Methanol
TAUROCHENODESOXYCHOLIC ACID, SODIUM SALT
taurochenodeoxycholic acid sodium salt
5BETA-CHOLAN-24-OIC ACID N-[2-SULFOETHYL]AMIDE-3ALPHA,7ALPHA-DIOL SODIUM SALT
2-([3-ALPHA,7-ALPHA-DIHYDROXY-24-OXO-5-BETA-CHOLAN-24-YL]AMINO)ETHANESULFONIC ACID
Taurochenodeoxycholic acid sodium, 10 mM in DMSO
Sodium taurochenodeoxycholate,2-([3α,7α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid sodium salt, 3α,7α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt, Taurochenodeoxy
Sodium 2-((4R)-4-((3R,7R,10S,13R,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)pentanamido)ethane-1-sulfonate
Taurochenodeoxycholic Acid-[d9] Sodium Salt
D4-Taurochenodeoxycholic Acid Sodium Salt
Ursodeoxycholic Impurity 15
D9-Taurochenodeoxycholic Acid Sodium Salt
Ethanesulfonic acid, 2-[[(3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1)
2-[(3ALPHA,7ALPHA-DIHYDROXY-24-OXO-5BETA-CHOLAN-24-YL)AMINO]ETHANESULFONIC ACID SODIUM SALT
Taurine goose deoxycholate sodium
Chenodeoxycholic Acid Impurity
TAUROCHENODEOXYCHOLIC ACID SODIUM SALT
Urosodeoxycholic Acid Impurity 15
2H9]-Taurochenodeoxycholic Acid Sodium Salt
Taurochenodeoxycholic Acid D4 Sodium Salt
5β-Cholanic Acid-3α-, 7α-Diol N-(2-Sulphoethyl)-Amide Sodium Salt
2-([3α,7α-dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid sodium salt
2-([3α,7α-Dihydroxy-24-Oxo-5β-Cholan-24-Yl]Amino)Ethanesulfonic Acid
5β-CHOLANIC ACID-3α, 7α-DIOL N-(2-SULPHOETHYL)-AMIDE
3ALPHA,7ALPHA-DIHYDROXY-5BETA-CHOLAN-24-OIC ACID N-[2-SULFOETHYL]AMIDE SODIUM SALT
Ethanesulfonic acid, 2-[[(3α,5β,7α,8ξ)-3,7-dihydroxy-24-oxocholan-24-yl]amino]-, sodium salt (1:1)
Sodium taurochenodeoxycholate-2,2,4,4-d4 >=98 atom % D, >=
Taurochenodeoxycholic acid sodium salt, 2-([3α,7α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid sodium salt, 3α,7α-Dihydroxy-5β-cholan-24-oic acid N-(2-sulfoethyl)amide sodium salt
SODIUM TAUROCHENODEOXYCHOLIC ACID
Sodium 2-{[(3α,5β,7α,8ξ)-3,7-dihydroxy-24-oxocholan-24-yl]amino}ethanesulfonate
MFCD00036745
Ethanesulfonic Acid,2-[[(3A,5B,7A-3,7-Dihydroxy-24-OxocholaN-24-Yl]Amino]-, Sodium Salt (1:1
Taurochenodeoxycholic Acid Sodium SaltQ: What is Taurochenodeoxycholic Acid Sodium Salt Q: What is the CAS Number of Taurochenodeoxycholic Acid Sodium Salt Q: What is the storage condition of Taurochenodeoxycholic Acid Sodium Salt
2-(((3α,5β,7α)-3,7-Dihydroxy-24-oxocholan-24-yl)amino)ethanesulfonic acid monosodium salt
NSC681055
Sodium Taurochenodeoxycholate (STCDC) extrapure
taurochenodeoxycholic acid soduim salt
5-BETA-CHOLANIC ACID-3-ALPHA, 7-ALPHA-DIOL N-(2-SULPHOETHYL)-AMIDE SODIUM SALT
Ethanesulfonic acid, 2-(((3α,5β,7α)-3,7-dihydroxy-24-oxocholan-24-yl)amino)-, monosodium salt
SODIUM TAUROCHENODEOXYCHOLATE
5BETA-CHOLANIC ACID-3ALPHA,7ALPHA-DIOL-24-N-(2-SULFOETHYL)-AMIDE SODIUM
TAUROCHENODEOXYCHOLIC ACID SODIUM
Description Taurochenodeoxycholic acid sodium salt (12-Deoxycholyltaurine sodium salt) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties[1][2].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro Taurochenodeoxycholic acid dramatically improves the apoptosis rate of NR8383 cells in a concentration-dependent manner. In the meantime, Taurochenodeoxycholic acid significantly augments PKC mRNA levels, activities and increases JNK, caspase-3 and caspase-8 mRNA expression levels, activities[1].
In Vivo Taurochenodeoxycholic acid (0.05, 0.1g/kg) decreases the pulmonary coefficient in the model mice and reduces the pathological damages on their lungs; it can decrease the expression levels of TNF-α and TIMP-2 in pulmonary tissues in the pulmonary fibrosis mice and has no significant effects on MMP2[2]. Taurochenodeoxycholic acid significantly normalizes the clinical inflammatory parameters, prevented indomethacin-induced increases in the biliary contents of secondary bile acids and hydrophobicity index, and tended to attenuate the intestinal inflammation[3]. Taurochenodeoxycholic acid significantly suppresses paw swelling and polyarthritis index, increases the loss body weight and index of thymus and spleen, and amends radiologic changes in AA rats. The overproduction and mRNA expression of TNF-α, IL-1β and IL-6 are remarkably suppressed in serum and synovium tissue of all TCDCA-treated rats[4].
References

[1]. Wang X, et al. Taurochenodeoxycholic acid induces NR8383 cells apoptosis via PKC/JNK-dependent pathway. Eur J Pharmacol. 2016 Sep 5;786:109-15.

[2]. Zhou C, et al. The effects of taurochenodeoxycholic acid in preventing pulmonary fibrosis in mice. Pak J Pharm Sci. 2013 Jul;26(4):761-5.

[3]. Uchida A, et al. Taurochenodeoxycholic acid ameliorates and ursodeoxycholic acid exacerbates small intestinal inflammation. Am J Physiol. 1997 May;272(5 Pt 1):G1249-57.

[4]. Liu M, et al. Effects of taurochenodeoxycholic acid on adjuvant arthritis in rats. Int Immunopharmacol. 2011 Dec;11(12):2150-8.
Density 1.164 g/mL at 25 °C(lit.)
Boiling Point 215 °C(lit.)
Molecular Formula C26H44NNaO6S
Molecular Weight 521.685
Flash Point 195 °F
Exact Mass 521.278687
PSA 135.14000
LogP 4.52640
Index of Refraction n20/D 1.558(lit.)
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport
WGK Germany 3
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title: CAS No. 6009-98-9 | Chemsrc address: https://m.chemsrc.com/en/baike/953469.html

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