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  • BioBioPha
  • China
  • Product Name: Dipsacoside B
  • Price: ¥Inquiry/5mg
  • Purity: 98.0%
  • Stocking Period: 10 Day
  • Contact: Xueping-Zheng


33289-85-9

33289-85-9 structure
33289-85-9 structure
  • Name: Dipsacoside B
  • Chemical Name: Dipsacoside B
  • CAS Number: 33289-85-9
  • Molecular Formula: C53H86O22
  • Molecular Weight: 1075.237
  • Catalog: Biochemical Plant extracts
  • Create Date: 2018-08-12 15:20:30
  • Modify Date: 2024-01-02 19:21:40
  • Dipsacoside B is a major bioactive saponin, which can be used as a marker.

Name Dipsacoside B
Synonyms Glycoside L-G3
MacranthoidinB
1-O-[(3β)-3-{[2-O-(6-Deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy}-23-hydroxy-28-oxoolean-12-en-28-yl]-6-O-β-D-glucopyranosyl-β-D-glucopyranose
Tauroside G3
β-D-Glucopyranose, 1-O-[(3β)-3-[[2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl]oxy]-23-hydroxy-28-oxoolean-12-en-28-yl]-6-O-β-D-glucopyranosyl-
Olean-12-en-28-oic acid, 3-((2-O-(6-deoxy-α-L-mannopyranosyl)-α-L-arabinopyranosyl)oxy)-23-hydroxy-, 6-O-β-D-glucopyranosyl-β-D-glucopyranosyl ester, (3β,4α)-
Description Dipsacoside B is a major bioactive saponin, which can be used as a marker.
Related Catalog
In Vivo A liquid chromatography-electrospray ionization-mass spectrometry method has been developed and validated for identification and quantification of four major bioactive saponins in rat plasma after oral administration of extraction of saponins from Flos Lonicerae, i.e., Macranthoidin B, Macranthoidin A, Dipsacoside B, and Macranthoside B. The retention time of Macranthoidin B, Macranthoidin A, Dipsacoside B, Macranthoside B and IS are 10.65, 12.11, 13.81, 23.31 and 5.47 min, respectively[1]. Taking Macranthoidins A, B, Dipsacoside B (saponins), sweroside (iridoids), and luteolin-7-O-d-glucoside (flavonoids) as markers, a method of ultra high performance liquid chromatography with triple quadrupole mass spectrometry is employed to determine their amounts in Lonicerae Flos, Lonicerae Japonicae Flos, and Lonicerae Japonicae Flos preparations[2].
Animal Admin Mice[1] Sprague-Dawley rats (220-250 g) are used. To calculate the administered dose of Macranthoidin B, Macranthoidin A, Dipsacoside B, and Macranthoside B, their contents in saponins extraction are quantitatively determined. One hundred milligrams of the dry powder is suspended in 100 mL 50% methanol (v/v), ultrasonically extracted for 40 min, and then cooled at room temperature; 50% methanol is added to compensate for the lost weight. Finally, 5 μL of this solution is injected into the HPLC system for analysis after filtration through a 0.45 μm membrane. The contents of Macranthoidin B, Macranthoidin A, Dipsacoside B, and Macranthoside B are found as 36.7, 6.59, 23.3 and 0.506 g/100 g extraction, respectively.
References

[1]. Chen CY, et al. Liquid chromatography-mass spectrometry analysis of macranthoidin B, macranthoidin A, Dipsacoside B, and macranthoside B in rat plasma for the pharmacokinetic investigation. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Jan 15;877(3):159-65.

[2]. Zhang X, et al. Rapid quantitative analysis of adulterant Lonicera species in preparations of Lonicerae Japonicae Flos. J Sep Sci. 2015 Dec;38(23):4014-20.

Density 1.5±0.1 g/cm3
Molecular Formula C53H86O22
Molecular Weight 1075.237
Exact Mass 1074.561035
PSA 353.90000
LogP 4.64
Index of Refraction 1.633
Hazard Codes Xn
Safety Phrases 24/25
Precursor  2

DownStream  1