Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3,5-Pyrazolidinedione,4-butyl-1-phenyl-
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Purity: 98.0%
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2210-63-1

2210-63-1 structure

Name: Mofebutazone
Chemical Name: mofebutazone
CAS Number: 2210-63-1
Molecular Formula: C₁₃H₁₆N₂O₂
Molecular Weight: 232.28
Catalog: Research Areas Inflammation/Immunology
Create Date: 2018-02-20 08:00:00
Modify Date: 2025-08-25 18:55:35
Mofebutazone, a monophenyl analogue of Phenylbutazone (DPB), is an anti-inflammatory compound. Mofebutazone can be used for research of asthma[1][2].

Name	mofebutazone
Synonyms	monophenylbutazone 4-Butyl-1-phenylpyrazolidin-3,5-dion mobutazon 4-butyl-1-phenyl-pyrazolidine-3,5-dione Mofebutazon monorheumetten reumatox MOFEBUTAZONE 2fdbp arcomonoltablets mobuzon monazan monobutyl

Description	Mofebutazone, a monophenyl analogue of Phenylbutazone (DPB), is an anti-inflammatory compound. Mofebutazone can be used for research of asthma[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. F.T. Delbeke, et al. Determination of mofebutazone and its 4-hydroxy metabolite in plasma and urine by high-performance liquid chromatography. Journal of Chromatography A. Volume 369, 1986, Pages 440-444 [2]. Khayyal MT,et al. Tolerability of mofebutazone in asthmatic patients. Int J Clin Pharmacol Res. 1995;15(4):145-51.

Density	1.14g/cm3
Molecular Formula	C₁₃H₁₆N₂O₂
Molecular Weight	232.28
Exact Mass	232.12100
PSA	49.41000
LogP	2.26460
Index of Refraction	1.541

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UQ8420000

CHEMICAL NAME :: 3,5-Pyrazolidinedione, 4-butyl-1-phenyl-

CAS REGISTRY NUMBER :: 2210-63-1

BEILSTEIN REFERENCE NO. :: 0213056

LAST UPDATED :: 199612

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C13-H16-N2-O2

MOLECULAR WEIGHT :: 232.31

WISWESSER LINE NOTATION :: T5VMNV EHJ CR& E4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1750 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PAHEAA Pharmaceutica Acta Helvetiae. (Schweizerische Apothekerzeitung, Postfach 3006, CH3000 Bern, 7, Switzerland) V.1- 1926- Volume(issue)/page/year: 39,155,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 848 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 14,347,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 700 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: SCPHA4 Scientia Pharmaceutica. (Oesterreichische Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria) V.1- 1930- Volume(issue)/page/year: 37,185,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 920 mg/kg

TOXIC EFFECTS :: Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: SCPHA4 Scientia Pharmaceutica. (Oesterreichische Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria) V.1- 1930- Volume(issue)/page/year: 37,185,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 233,365,1958

HS Code	2933990090

39520-22-4

100-63-0

2210-63-1

Literature: US2790808 , ; Helvetica Chimica Acta, , vol. 36, p. 75,79, 81

100-63-0

133-08-4

2210-63-1

Literature: Canadian Journal of Research, Section B: Chemical Sciences, , vol. 28, p. 720,725 Australian Journal of Chemistry, , vol. 27, p. 2447,2448

Precursor 3
39520-22-4 100-63-0 133-08-4
DownStream 1
55228-09-6

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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