Mofebutazone

Modify Date: 2024-01-09 16:58:51

Mofebutazone Structure
Mofebutazone structure
Common Name Mofebutazone
CAS Number 2210-63-1 Molecular Weight 232.28
Density 1.14g/cm3 Boiling Point N/A
Molecular Formula C13H16N2O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mofebutazone


Mofebutazone, a monophenyl analogue of Phenylbutazone (DPB), is an anti-inflammatory compound. Mofebutazone can be used for research of asthma[1][2].

 Names

Name mofebutazone
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.14g/cm3
Molecular Formula C13H16N2O2
Molecular Weight 232.28
Exact Mass 232.12100
PSA 49.41000
LogP 2.26460
Index of Refraction 1.541

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ8420000
CHEMICAL NAME :
3,5-Pyrazolidinedione, 4-butyl-1-phenyl-
CAS REGISTRY NUMBER :
2210-63-1
BEILSTEIN REFERENCE NO. :
0213056
LAST UPDATED :
199612
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C13-H16-N2-O2
MOLECULAR WEIGHT :
232.31
WISWESSER LINE NOTATION :
T5VMNV EHJ CR& E4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1750 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PAHEAA Pharmaceutica Acta Helvetiae. (Schweizerische Apothekerzeitung, Postfach 3006, CH3000 Bern, 7, Switzerland) V.1- 1926- Volume(issue)/page/year: 39,155,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
848 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia, Italy) V.8-43 1953-88 For publisher information, see FRMCE8 Volume(issue)/page/year: 14,347,1959
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
SCPHA4 Scientia Pharmaceutica. (Oesterreichische Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria) V.1- 1930- Volume(issue)/page/year: 37,185,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
920 mg/kg
TOXIC EFFECTS :
Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
SCPHA4 Scientia Pharmaceutica. (Oesterreichische Apotheker-Verlagsgesellschaft MBH, Spitalgasse 31, 1094 Vienna 9, Austria) V.1- 1930- Volume(issue)/page/year: 37,185,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 233,365,1958

 Safety Information

HS Code 2933990090

 Synthetic Route

~%

Mofebutazone Structure

Mofebutazone

CAS#:2210-63-1

Literature: US2790808 , ; Helvetica Chimica Acta, , vol. 36, p. 75,79, 81

~%

Mofebutazone Structure

Mofebutazone

CAS#:2210-63-1

Literature: Canadian Journal of Research, Section B: Chemical Sciences, , vol. 28, p. 720,725 Australian Journal of Chemistry, , vol. 27, p. 2447,2448

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

monophenylbutazone
4-Butyl-1-phenylpyrazolidin-3,5-dion
mobutazon
4-butyl-1-phenyl-pyrazolidine-3,5-dione
Mofebutazon
monorheumetten
reumatox
MOFEBUTAZONE
2fdbp
arcomonoltablets
mobuzon
monazan
monobutyl