18865-38-8
18865-38-8 structure
- Name: Glycinexylidide
- Chemical Name: glycinexylidide
- CAS Number: 18865-38-8
- Molecular Formula: C10H14N2O
- Molecular Weight: 178.23
- Catalog: Signaling Pathways MAPK/ERK Pathway ERK
- Create Date: 2018-12-31 15:43:31
- Modify Date: 2024-01-03 15:22:55
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Glycinexylidide (GX) is the active metabolite of Lidocaine. Lidocaine is a local anesthetic that inhibits sodium channels involving complex voltage and dependence. Lidocaine also reduces the growth, migration and invasion of gastric cancer cells. Glycinexylidide has research potential for use in anesthesia, cancer, and cardiovascular disease[1].
| Name | glycinexylidide |
|---|---|
| Synonyms |
Glycinexylidide
2-AMINO-N-(2,6-DIMETHYLPHENYL)ACETAMIDE |
| Description | Glycinexylidide (GX) is the active metabolite of Lidocaine. Lidocaine is a local anesthetic that inhibits sodium channels involving complex voltage and dependence. Lidocaine also reduces the growth, migration and invasion of gastric cancer cells. Glycinexylidide has research potential for use in anesthesia, cancer, and cardiovascular disease[1]. |
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| Related Catalog | |
| References |
| Density | 1.122g/cm3 |
|---|---|
| Boiling Point | 323.5ºC at 760mmHg |
| Melting Point | 92 °C |
| Molecular Formula | C10H14N2O |
| Molecular Weight | 178.23 |
| Flash Point | 149.4ºC |
| Exact Mass | 178.11100 |
| PSA | 55.12000 |
| LogP | 1.97390 |
| Vapour Pressure | 0.000261mmHg at 25°C |
| HS Code | 2924299090 |
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| Literature: CORUS PHARMA Patent: WO2005/25498 A2, 2005 ; Location in patent: Page/Page column 49 ; |
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| Literature: Medicinal Chemistry Research, , vol. 22, # 10 p. 4708 - 4714 |
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| Literature: Medicinal Chemistry Research, , vol. 22, # 10 p. 4708 - 4714 |
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| Literature: Biochemical Pharmacology, , vol. 82, # 7 p. 789 - 796 |
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| Literature: Pharmazie, , vol. 35, # 5-6 p. 278 - 284 |
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| Literature: Journal of Pharmaceutical Sciences, , vol. 66, # 8 p. 1180 - 1190 |
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| Literature: Journal of Pharmaceutical Sciences, , vol. 74, # 11 p. 1219 - 1224 |
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18865-38-8
Detail
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| Literature: Journal of Pharmaceutical Sciences, , vol. 74, # 11 p. 1219 - 1224 |
| Precursor 7 | |
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| DownStream 2 | |
![N-[2-(2,6-dimethylanilino)-2-oxoethyl]-1-hydroxy-2,2,5,5-tetramethylpyrrolidine-3-carboxamide structure](https://www.chemsrc.com/caspic/446/102132-47-8.png)
![N-(2,6-dimethylphenyl)-2-[1,1,2,2,2-pentadeuterioethyl(2,2,2-trideuterioethyl)amino]acetamide structure](https://www.chemsrc.com/caspic/483/851528-09-1.png)
| HS Code | 2924299090 |
|---|---|
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |