471-74-9

471-74-9 structure

Name: Sandaracopimaric acid
Chemical Name: .δ.8(14)-Isopimaric acid
CAS Number: 471-74-9
Molecular Formula: C₂₀H₃₀O₂
Molecular Weight: 302.451
Catalog: Research Areas Cardiovascular Disease
Create Date: 2018-08-08 16:14:55
Modify Date: 2024-01-06 10:06:28
Sandaracopimaric acid is a diterpenoid with anti-inflammatory effect. Sandaracopimaric acid reduces the contraction of phenylephrine-induced pulmonary arteries with an EC50 of 43.93 μM[1][2].

Name	.δ.8(14)-Isopimaric acid
Synonyms	Pimara-8(14),15-dien-18-oic acid (ent)-pimara-8(14),15-dien-19-oic acid pimaradienoic acid (-)-pimara-8(14),15-diene-19-oic acid 1-Phenanthrenecarboxylic acid, 7-ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-1,4a,7-trimethyl- 7-Ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-1,4a,7-trimethyl-1-phenanthrenecarboxylic Acid 13-Methyl-17-norabieta-8(14),15-diene-18-oic acid (-)-pimara-8(14),15-dien-19-oic acid

Description	Sandaracopimaric acid is a diterpenoid with anti-inflammatory effect. Sandaracopimaric acid reduces the contraction of phenylephrine-induced pulmonary arteries with an EC50 of 43.93 μM[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Wenyan Gao, et al. Dehydroabietic acid isolated from Commiphora opobalsamum causes endothelium-dependent relaxation of pulmonary artery via PI3K/Akt-eNOS signaling pathway. Molecules. 2014 Jun 23;19(6):8503-17. [2]. Masao Takei, et al. Diterpenes drive Th1 polarization depending on IL-12. Int Immunopharmacol. 2008 Nov;8(11):1602-8.