Sandaracopimaric acid

Modify Date: 2026-07-13 23:12:21

Sandaracopimaric acid Structure
Sandaracopimaric acid structure
Common Name Sandaracopimaric acid
CAS Number 471-74-9 Molecular Weight 302.451
Density 1.1±0.1 g/cm3 Boiling Point 413.2±45.0 °C at 760 mmHg
Molecular Formula C20H30O2 Melting Point N/A
MSDS N/A Flash Point 198.7±23.4 °C

 Use of Sandaracopimaric acid


Sandaracopimaric acid is a diterpenoid with anti-inflammatory effect. Sandaracopimaric acid reduces the contraction of phenylephrine-induced pulmonary arteries with an EC50 of 43.93 μM[1][2].

 Names

Name .δ.8(14)-Isopimaric acid
Synonym More Synonyms

 Sandaracopimaric acid Biological Activity

Description Sandaracopimaric acid is a diterpenoid with anti-inflammatory effect. Sandaracopimaric acid reduces the contraction of phenylephrine-induced pulmonary arteries with an EC50 of 43.93 μM[1][2].
Related Catalog
References

[1]. Wenyan Gao, et al. Dehydroabietic acid isolated from Commiphora opobalsamum causes endothelium-dependent relaxation of pulmonary artery via PI3K/Akt-eNOS signaling pathway. Molecules. 2014 Jun 23;19(6):8503-17.

[2]. Masao Takei, et al. Diterpenes drive Th1 polarization depending on IL-12. Int Immunopharmacol. 2008 Nov;8(11):1602-8.

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 413.2±45.0 °C at 760 mmHg
Molecular Formula C20H30O2
Molecular Weight 302.451
Flash Point 198.7±23.4 °C
Exact Mass 302.224579
PSA 37.30000
LogP 6.60
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.538
InChIKey MHVJRKBZMUDEEV-KRFUXDQASA-N
SMILES C=CC1(C)C=C2CCC3C(C)(C(=O)O)CCCC3(C)C2CC1

 Sandaracopimaric acidBioassay

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Name: Cytotoxicity against human SW480 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: SW480
External Id: CHEMBL2388323
Name: Anxiolytic activity in C57Bl/6N mouse assessed as ambulation distance at 30 mg/kg, ip...
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL2148430
Name: Cytotoxicity against human Raji cells assessed as cell viability at 1000 molar ratio ...
Source: ChEMBL
Target: Raji
External Id: CHEMBL1035059
Name: Cytotoxicity against human HL60 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: HL-60
External Id: CHEMBL2388327
Name: Inhibition of 12-O-tetradecanoylphorbol 13-acetate-induced Epstein-Barr virus early a...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1035057
Name: Cytotoxicity against human SMMC7721 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: SMMC-7721
External Id: CHEMBL2388326
Name: Inhibition of 12-O-tetradecanoylphorbol 13-acetate-induced Epstein-Barr virus early a...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1035058
Name: Cytotoxicity against human MCF7 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: MCF7
External Id: CHEMBL2388325
Name: Inhibition of 12-O-tetradecanoylphorbol 13-acetate-induced Epstein-Barr virus early a...
Source: ChEMBL
Target: N/A
External Id: CHEMBL1035055
Name: Cytotoxicity against human A549 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: A549
External Id: CHEMBL2388324
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 Synonyms

Pimara-8(14),15-dien-18-oic acid
(ent)-pimara-8(14),15-dien-19-oic acid
pimaradienoic acid
(-)-pimara-8(14),15-diene-19-oic acid
7-Ethenyl-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-1,4a,7-trimethyl-1-phenanthrenecarboxylic Acid
13-Methyl-17-norabieta-8(14),15-diene-18-oic acid
(-)-pimara-8(14),15-dien-19-oic acid
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