DC Chemicals Limited
China
Product Name: Crimidine
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

535-89-7

535-89-7 structure

535-89-7 structure

Name: Crimidine
Chemical Name: crimidine
CAS Number: 535-89-7
Molecular Formula: C₇H₁₀ClN₃
Molecular Weight: 171.627
Catalog: Chemical pesticide Insecticide Rodenticide
Create Date: 2018-08-11 18:22:48
Modify Date: 2024-01-11 13:00:28
Crimidine is a convulsant poison used as a rodenticide. Crimidine was originally known by its product name, Castrix. It was originally produced in the 1940s by the conglomerate, IG Farben.

Name	crimidine
Synonyms	2-chloro-N,N,6-trimethylpyrimidin-4-amine Crimidin 2-Chloro-4-(dimethylamino)-6-methylpyrimidine Crimidina [Italian] 2-Chloro-4-dimethylamino-6-methylpyrimidine Crimidine Crimidine [ISO:BSI] MFCD00055517 Caswell No. 188 2-chloro-4-dimethylamino-6-methyl-pyrimidine 4-Pyrimidinamine, 2-chloro-N,N,6-trimethyl- Castrix EINECS 208-622-6 Crimidin [German] 2-dimethylamino-4-chloro-6-methylpyrimidine (2-Chlor-6-methyl-pyrimidin-4-yl)-dimethyl-amin 2-Chlor-N,N,6-trimethylpyrimidin-4-amin 2-Chloro-N,N,6-trimethyl-4-pyrimidinamine Crimidina T6N CNJ BG DN1&1 F1 (2-chloro-6-methyl-pyrimidin-4-yl)-dimethyl-amine

Density	1.2±0.1 g/cm3
Boiling Point	291.2±20.0 °C at 760 mmHg
Melting Point	87ºC
Molecular Formula	C₇H₁₀ClN₃
Molecular Weight	171.627
Flash Point	129.9±21.8 °C
Exact Mass	171.056320
PSA	29.02000
LogP	1.73
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.568

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UV8050000

CHEMICAL NAME :: Pyrimidine, 2-chloro-4-(dimethylamino)-6-methyl-

CAS REGISTRY NUMBER :: 535-89-7

BEILSTEIN REFERENCE NO. :: 0127995

LAST UPDATED :: 199612

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C7-H10-Cl-N3

MOLECULAR WEIGHT :: 171.65

WISWESSER LINE NOTATION :: T6N CNJ BG DN1&1 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1250 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GUCHAZ Guide to the Chemicals Used in Crop Protection. (Information Canada, 171 Slater St., Ottawa, Ont., Canada) Volume(issue)/page/year: 6,139,1973

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85JFAN "Agrochemicals Handbook," with updates, Hartley, D., and H. Kidd, eds., Nottingham, Royal Soc. of Chemistry, 1983-86 Volume(issue)/page/year: A099,1983

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 37,307,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1250 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971 Volume(issue)/page/year: -,422,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1200 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85KYAH "Merck Index; an Encyclopedia of Chemicals, Drugs, and Biologicals", 11th ed., Rahway, NJ 07065, Merck & Co., Inc. 1989 Volume(issue)/page/year: 11,405,1989

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 420 ug/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 37,307,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 500 ug/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 37,307,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969 Volume(issue)/page/year: 5,59,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 37,307,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 5 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 30ZDA9 "Chemistry of Pesticides," Melnikov, N.N., New York, Springer-Verlag New York, Inc., 1971 Volume(issue)/page/year: -,422,1971

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 2660 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PCOC** Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. (Topeka, KS) Volume(issue)/page/year: -,202,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 2660 ug/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 37,307,1948

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 22500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85DPAN "Wirksubstanzen der Pflanzenschutz und Schadlingsbekampfungsmittel," Perkow, W., Berlin, Verlag Paul Parey, 1971-1976 Volume(issue)/page/year: -,-,1971/1976

Symbol	GHS06
Signal Word	Danger
Hazard Statements	H300
Precautionary Statements	P301 + P310 + P330
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T+:Verytoxic;
Risk Phrases	R28
Safety Phrases	S36/37-S45
RIDADR	UN 2811
RTECS	UV8050000
Packaging Group	I
Hazard Class	6.1(a)
HS Code	2933599017

5424-21-5 structure

5424-21-5

124-40-3 structure

124-40-3

~41%

535-89-7 structure

535-89-7

Literature: Semple, Graeme; Tran, Thuy-Anh; Kramer, Bryan; Hsu, Debbie; Han, Sangdon; Choi, Juyi; Vallar, Pureza; Casper, Martin D.; Zou, Ning; Hauser, Erin K.; Thomsen, William; Whelan, Kevin; Sengupta, Dipanjan; Morgan, Michael; Sekiguchi, Yoshinori; Kanuma, Kosuke; Chaki, Shigeyuki; Grottick, Andrew J. Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 21 p. 6166 - 6171

5424-21-5 structure

5424-21-5

124-40-3 structure

124-40-3

~%

535-89-7 structure

535-89-7

5734-62-3 structure

5734-62-3

Literature: WO2005/95357 A2, ; Page/Page column 137; 138 ; WO 2005/095357 A2

Precursor 2
5424-21-5 124-40-3
DownStream 1
77940-23-9

HS Code	2933599017
Summary	2933599017 2-chloro-n,n,6-trimethylpyrimidin-4-amine。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%