DC Chemicals Limited
China
Product Name: Terutroban
Price: $500.0/100mg $900.0/250mg $1700.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

165538-40-9

165538-40-9 structure

165538-40-9 structure

Name: S 18886
Chemical Name: 3-[(6R)-6-[(4-chlorophenyl)sulfonylamino]-2-methyl-5,6,7,8-tetrahydronaphthalen-1-yl]propanoic acid
CAS Number: 165538-40-9
Molecular Formula: C₂₀H₂₂ClNO₄S
Molecular Weight: 407.91100
Catalog: Signaling Pathways GPCR/G Protein Prostaglandin Receptor
Create Date: 2017-10-02 22:15:23
Modify Date: 2024-01-29 16:25:26
Terutroban is a thromboxane-prostaglandin receptor antagonist.

Name	3-[(6R)-6-[(4-chlorophenyl)sulfonylamino]-2-methyl-5,6,7,8-tetrahydronaphthalen-1-yl]propanoic acid
Synonyms	Terutroban [INN] UNII-A6WX9391D8 terutroban 3-{6-[(4-chlorophenylsulphonyl)amino]-2-methyl-5,6,7,8-tetrahydronaphth-1-yl}-propionic acid

Description	Terutroban is a thromboxane-prostaglandin receptor antagonist.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Prostaglandin Receptor Research Areas >> Cardiovascular Disease
References	[1]. De La Cruz JP, et al. Effects of terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, on retinal vascularity in diabetic rats. Diabetes Metab Res Rev. 2012 Feb;28(2):132-138. [2]. Bots ML, et al. Thromboxane prostaglandin receptor antagonist and carotid atherosclerosis progression in patients with cerebrovascular disease of ischemic origin: a randomized controlled trial. Stroke. 2014 Aug;45(8):2348-2353. [3]. Lesault PF, et al. Daily administration of the TP receptor antagonist terutroban improved endothelial function in high-cardiovascular-risk patients with atherosclerosis. Br J Clin Pharmacol.2011 Jun;71(6):844-851.

Density	1.389g/cm3
Boiling Point	591.818ºC at 760 mmHg
Molecular Formula	C₂₀H₂₂ClNO₄S
Molecular Weight	407.91100
Flash Point	311.721ºC
Exact Mass	407.09600
PSA	91.85000
LogP	4.97310
Vapour Pressure	0mmHg at 25°C
Index of Refraction	1.637
Storage condition	2-8℃

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
RIDADR	NONH for all modes of transport