- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Hydroxy-PEG3-(CH2)2-Boc
- Price: ￥880.0/1g ￥3060.0/5g
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Hydroxy-PEG3-(CH2)2-Boc
- Price:
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: TERT-BUTYL 12-HYDROXY-4 7 10-TRIOXA-
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
186020-66-6
186020-66-6 structure
- Name: Hydroxy-PEG3-(CH2)2-Boc
- Chemical Name: tert-butyl 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]propanoate
- CAS Number: 186020-66-6
- Molecular Formula: C13H26O6
- Molecular Weight: 278.34200
- Catalog: Signaling Pathways Antibody-drug Conjugate ADC Linker
- Create Date: 2019-01-01 17:26:24
- Modify Date: 2024-01-03 13:47:18
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Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)[1].
| Name | tert-butyl 3-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]propanoate |
|---|---|
| Synonyms |
Hydroxy-PEG3-t-butyl ester
12-hydroxy-4,7,10-trioxadodecanoic acid tert-butyl ester tert-Butyl triethylene glycol-O-propionate tert-Butyl 12-hydroxy-4,7,10-trioxadodecanoate |
| Description | Hydroxy-PEG2-(CH2)2-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG2-(CH2)2-Boc is extracted from patent WO2004008101A2 (compound 196)[1]. |
|---|---|
| Related Catalog | |
| Target |
Non-cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
| Density | 1.057g/cm3 |
|---|---|
| Boiling Point | 365.8ºC at 760 mmHg |
| Molecular Formula | C13H26O6 |
| Molecular Weight | 278.34200 |
| Flash Point | 125.2ºC |
| Exact Mass | 278.17300 |
| PSA | 74.22000 |
| LogP | 0.76030 |
| Vapour Pressure | 7.78E-07mmHg at 25°C |
| Index of Refraction | 1.45 |
| Personal Protective Equipment | Eyeshields;Gloves |
|---|---|
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
| HS Code | 2918990090 |
|
~94%
186020-66-6 |
| Literature: Wilbur, D. Scott; Pathare, Pradip M.; Hamlin, Donald K.; Wan, Feng Patent: US2006/228325 A1, 2006 ; Location in patent: Page/Page column 63 ; |
| Precursor 2 | |
|---|---|
| DownStream 1 | |
| HS Code | 2918990090 |
|---|---|
| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |