1571-30-8

1571-30-8 structure

Name: 8-Hydroxyquinoline-2-Carboxylic Acid
Chemical Name: 8-hydroxyquinoline-2-carboxylic acid
CAS Number: 1571-30-8
Molecular Formula: C₁₀H₇NO₃
Molecular Weight: 189.167
Catalog: Pharmaceutical intermediate Heterocyclic compound Quinoline compound
Create Date: 2018-07-26 11:45:34
Modify Date: 2024-01-08 12:32:26
BAY32-5915 is a potent IKKα inhibitor with an IC50 value of 60 nM. BAY32-5915 has not affect Doxorubicin (HY-15142A)-induced NF-κB activation[1].

Name	8-hydroxyquinoline-2-carboxylic acid
Synonyms	8-hydroxyquinoline-2-carboxylic acid 8-Hydroxy-2-quinolinecarboxylic acid 2-Quinolinecarboxylic acid, 8-hydroxy- MFCD00168972 Quinaldic acid, 8-hydroxy- 8-Hydroxyquinaldic acid

Description	BAY32-5915 is a potent IKKα inhibitor with an IC50 value of 60 nM. BAY32-5915 has not affect Doxorubicin (HY-15142A)-induced NF-κB activation[1].
Related Catalog	Signaling Pathways >> NF-κB >> IKK Research Areas >> Cancer
Target	IKK-α:60 nM (IC50)
In Vitro	BAY32-5915 (50-200 μM) has no significant inhibitory effect on NF-κB activity in melanoma cells[1].

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - tumors

REFERENCE :: ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 108,924,1963 *** REVIEWS *** TOXICOLOGY REVIEW AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,6,1971

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	UZ9450000
HS Code	2933499090

HS Code	2933499090
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%