3055-94-5

3055-94-5 structure

Name: Triethylene glycol monododecyl ether
Chemical Name: 2-[2-(2-dodecoxyethoxy)ethoxy]ethanol
CAS Number: 3055-94-5
Molecular Formula: C₁₈H₃₈O₄
Molecular Weight: 318.492
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-02-22 08:00:00
Modify Date: 2025-08-27 20:17:56
Triethylene glycol monododecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	2-[2-(2-dodecoxyethoxy)ethoxy]ethanol
Synonyms	Lauryltriglycol ether Triethylene glycol monododecyl ether triiethylene glycol mondodecyl ether PEG-3 Lauryl ether Ethanol, 2-[2-[2-(dodecyloxy)ethoxy]ethoxy]- C12E3 Dodecyl triethylene glycol ether Dodecyltriglycol Polyoxyethylene (3) lauryl ether Dodecyltriglycol 2-{2-[2-(Dodecyloxy)ethoxy]ethoxy}ethanol TRIETHYLENE GLYCOL MONO-N-DODECYL ETHER triethyleneglycol monododecyl ether Dodecyl triethylene glycol ether Lauryl triethoxylate MFCD00042659 Detergent Screening EINECS 221-280-2 Triethylene glycol dodecyl ether Triethyleneglycol monododecyl ether 1 mM Lauryl alcohol triglycol ether

Description	Triethylene glycol monododecyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.

Density	0.9±0.1 g/cm3
Boiling Point	412.0±25.0 °C at 760 mmHg
Molecular Formula	C₁₈H₃₈O₄
Molecular Weight	318.492
Flash Point	202.9±23.2 °C
Exact Mass	318.277008
PSA	47.92000
LogP	4.33
Vapour Pressure	0.0±2.2 mmHg at 25°C
Index of Refraction	1.451
Storage condition	2-8°C
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,431,1976

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H319
Precautionary Statements	P305 + P351 + P338
Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi: Irritant;
Risk Phrases	R36
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
RTECS	KK7870000
HS Code	2909499000

143-15-7

112-27-6

3055-94-5

Literature: Journal of Organic Chemistry, , vol. 25, p. 439 - 444

112-53-8

3055-94-5

Literature: Bulletin des Societes Chimiques Belges, , vol. 65, p. 453,470

75-21-8

3055-93-4

3055-94-5

Literature: Bulletin des Societes Chimiques Belges, , vol. 65, p. 453,470

4536-30-5

3055-94-5

Literature: Bulletin des Societes Chimiques Belges, , vol. 65, p. 453,470

HS Code	2909499000
Summary	2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%