4-Vinylcyclohexene

Modify Date: 2026-07-02 13:14:19

4-Vinylcyclohexene structure	Common Name	4-Vinylcyclohexene
	CAS Number	100-40-3	Molecular Weight	108.181
	Density	0.9±0.1 g/cm3	Boiling Point	128.9±20.0 °C at 760 mmHg
	Molecular Formula	C₈H₁₂	Melting Point	-101 °C
	MSDS	Chinese USA	Flash Point	20.0±0.0 °C
	Symbol	GHS02, GHS07, GHS08	Signal Word	Danger

Summary: 4-Vinyl-1-Cyclohexene (Chinese name: 4-乙烯基环己烯, CAS number: 100-40-3), molecular formula: C8H12, molecular weight: 108.181. Slightly yellow liquid,熔点-101 °C,沸点128.9±20.0 °C, density 0.9±0.1 g/cm3. For research-use only, not for medical or clinical usage.

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	4-Vinyl-1-Cyclohexene
Synonym	More Synonyms

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	0.9±0.1 g/cm3
Boiling Point	128.9±20.0 °C at 760 mmHg
Melting Point	-101 °C
Molecular Formula	C₈H₁₂
Molecular Weight	108.181
Flash Point	20.0±0.0 °C
Exact Mass	108.093903
LogP	3.31
Vapour density	3.76 (vs air)
Vapour Pressure	12.7±0.1 mmHg at 25°C
Index of Refraction	1.544
InChIKey	BBDKZWKEPDTENS-UHFFFAOYSA-N
SMILES	C=CC1CC=CCC1

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

4-Vinylcyclohexene MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GW6650000

CHEMICAL NAME :: 1-Cyclohexene, 4-vinyl-

CAS REGISTRY NUMBER :: 100-40-3

BEILSTEIN REFERENCE NO. :: 1901553

LAST UPDATED :: 199712

DATA ITEMS CITED :: 30

MOLECULAR FORMULA :: C8-H12

MOLECULAR WEIGHT :: 108.20

WISWESSER LINE NOTATION :: L6UTJ D1U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3080 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8000 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 27 gm/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 11,279,1976

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 20 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 17500 mg/kg/14D-I

TOXIC EFFECTS :: Related to Chronic Data - death

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-303,1986

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 52 gm/kg/13W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Related to Chronic Data - death

REFERENCE :: JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 21,493,1987

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1500 ppm/6H/13W-I

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 32,1,1996

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 17500 mg/kg/14D-I

TOXIC EFFECTS :: Related to Chronic Data - death

REFERENCE :: JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 21,493,1987

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 78 gm/kg/13W-I

TOXIC EFFECTS :: Related to Chronic Data - death

REFERENCE :: JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 21,493,1987

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1000 ppm/6H/4W-I

TOXIC EFFECTS :: Related to Chronic Data - death

REFERENCE :: TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 15,182,1995

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1000 ppm/6H/13W-I

TOXIC EFFECTS :: Blood - pigmented or nucleated red blood cells Blood - changes in erythrocyte (RBC) count Related to Chronic Data - death

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 32,1,1996 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 103 gm/kg/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Reproductive - Tumorigenic effects - ovarian tumors

REFERENCE :: JTEHD6 Journal of Toxicology and Environmental Health. (Hemisphere Pub., 1025 Vermont Ave., NW, Washington, DC 20005) V.1- 1975/76- Volume(issue)/page/year: 21,507,1987

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 16 gm/kg/54W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

REFERENCE :: JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 31,41,1963

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 103 gm/kg/2Y-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Reproductive - Tumorigenic effects - ovarian tumors

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-303,1986

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 206 gm/kg/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Blood - lymphoma, including Hodgkin's disease

REFERENCE :: NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-303,1986 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 24 gm/kg

SEX/DURATION :: female 30 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - ovaries, fallopian tubes

REFERENCE :: TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 12,433,1992

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 19500 mg/kg

SEX/DURATION :: female 30 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Maternal Effects - ovaries, fallopian tubes

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 119,302,1993 *** REVIEWS *** ACGIH TLV-Animal carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 0.44 mg/m3 (0.1 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 39,181,1986 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 60,347,1994 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 39,181,1986 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 60,347,1994 IARC Cancer Review:Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 60,347,1994

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Symbol	GHS02, GHS07, GHS08
Signal Word	Danger
Hazard Statements	H225-H304-H315-H351-H361-H412
Precautionary Statements	P201-P210-P273-P301 + P310-P308 + P313-P331
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	F:Highlyflammable;Xn:Harmful;
Risk Phrases	R11;R38;R40;R52/53
Safety Phrases	S16-S33-S36/37
RIDADR	UN 1993 3/PG 2
WGK Germany	2
RTECS	GW6650000
Packaging Group	II
Hazard Class	3.1
HS Code	2902199090

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 9
CAS#:106-99-0 butadiene CAS#:16388-31-1 4-Ethinylcyclohexen CAS#:3322-93-8 1,2-Dibromo-4-(... CAS#:51-80-9 Bis(dimethylami...
CAS#:110-89-4 Piperidine CAS#:934-79-2 4-Vinyl-1,2-dib... CAS#:87-72-9 L-Arabinopyranose CAS#:108-24-7 Ethanoic anhydride
CAS#:1552-12-1 1,5-cyclooctadiene
DownStream 10
CAS#:5441-51-0 4-Ethylcyclohexanone CAS#:64847-85-4 (S)-(-)-3-ethyl... CAS#:3322-93-8 1,2-Dibromo-4-(... CAS#:4442-85-7 2-Cyclohexyleth...
CAS#:923-42-2 1,2,4-Butanetri... CAS#:64-18-6 Formic Acid CAS#:110-15-6 Succinic acid CAS#:99-14-9 Tricarballylic acid
CAS#:123-76-2 Levulinic acid CAS#:21130-56-3 4-(2-iodoethyl)...

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2902199090
Summary	2902199090 other cyclanes, cyclenes and cyclotherpenes。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

Impact of environmental exposures on ovarian function and role of xenobiotic metabolism during ovotoxicity.

Toxicol. Appl. Pharmacol. 261(3) , 227-35, (2012)

The mammalian ovary is a heterogeneous organ and contains oocyte-containing follicles at varying stages of development. The most immature follicular stage, the primordial follicle, comprises the ovari...

Effect of bcl-2 overexpression in mice on ovotoxicity caused by 4-vinylcyclohexene.

Toxicol. Appl. Pharmacol. 215(1) , 51-6, (2006)

The occupational chemical 4-vinylcyclohexene (VCH) destroys small preantral ovarian follicles in mice following repeated daily dosing. The cell survival gene bcl-2 is thought to protect against follic...

Role of induction of specific hepatic cytochrome P450 isoforms in epoxidation of 4-vinylcyclohexene.

Drug Metab. Dispos. 29(9) , 1236-42, (2001)

4-Vinyl-1-cyclohexene (VCH) is ovotoxic in B6C3F(1) mice but not in Fischer-344 rats, which can be partially attributed to greater formation of toxic epoxides from VCH in mice compared with rats. Sinc...

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

4-Vinylcyclohex-1-ene

EINECS 202-848-9

4-Vinylcyclohexene

4-Ethenylcyclohexene

4-Vinyl-1-cyclohexene,stabilized

MFCD00001576

L6UTJ D1U1

4-Vinyl-1-cyclohexene

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the SMILES notation of 4-Vinyl-1-Cyclohexene?

A: SMILES notation of 4-Vinyl-1-Cyclohexene is C=CC1CC=CCC1.

Q: What is the InChIKey of 4-Vinyl-1-Cyclohexene?

A: InChIKey of 4-Vinyl-1-Cyclohexene is BBDKZWKEPDTENS-UHFFFAOYSA-N.

Q: What is the LogP of 4-Vinyl-1-Cyclohexene?

A: LogP of 4-Vinyl-1-Cyclohexene is 3.31.

Q: What is the boiling point of 4-Vinyl-1-Cyclohexene?

A: Boiling point of 4-Vinyl-1-Cyclohexene is 128.9±20.0 °C at 760 mmHg.

Q: What is the CAS number of 4-Vinyl-1-Cyclohexene?

A: CAS number of 4-Vinyl-1-Cyclohexene is 100-40-3.

Q: What is the English name of 4-Vinyl-1-Cyclohexene?

A: The English name of 4-Vinyl-1-Cyclohexene is 4-Vinyl-1-Cyclohexene.

Q: What are the downstream products of 4-Vinyl-1-Cyclohexene?

A: Related downstream products(CAS) of 4-Vinyl-1-Cyclohexene: 5441-51-0;64847-85-4;3322-93-8;4442-85-7;923-42-2;64-18-6;110-15-6;99-14-9;123-76-2;21130-56-3.

Q: What is the molecular weight of 4-Vinyl-1-Cyclohexene?

A: Molecular weight of 4-Vinyl-1-Cyclohexene is 108.181.

Q: What is the molecular formula of 4-Vinyl-1-Cyclohexene?

A: Molecular formula of 4-Vinyl-1-Cyclohexene is C8H12.

Q: What is the melting point of 4-Vinyl-1-Cyclohexene?

A: Melting point of 4-Vinyl-1-Cyclohexene is -101 °C.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

Henan Tianfu Chemical Co., Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 4-Vinylcyclohexene
Price: Check
Purity: 97.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Cyclohexene, 4-ethenyl-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 100-40-3 4-Vinyl-1-cyclohexene
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Get all suppliers and price by the below link:

4-Vinylcyclohexene suppliers

4-Vinylcyclohexene price

4-Vinylcyclohexene

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Articles26

Synonyms

4-Vinylcyclohexene | FAQ

4-Vinylcyclohexenefactory

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.