Ceramides Mixture structure
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Common Name | Ceramides Mixture | ||
|---|---|---|---|---|
| CAS Number | 100403-19-8 | Molecular Weight | 397.63488 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H47NO3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Ceramides MixtureCeramides Mixture is an endogenous ceramide and consists of hydroxy and non-hydroxy fatty acid-containing ceramides. Ceramides Mixture is a main lipid component of the permeability barrier in epidermis. Ceramides Mixture is involved in the regulation of growth inhibition, cell cycle arrest, and modulation of telomerase activity[1][2]. |
| Name | Ceramides |
|---|---|
| Synonym | More Synonyms |
| Description | Ceramides Mixture is an endogenous ceramide and consists of hydroxy and non-hydroxy fatty acid-containing ceramides. Ceramides Mixture is a main lipid component of the permeability barrier in epidermis. Ceramides Mixture is involved in the regulation of growth inhibition, cell cycle arrest, and modulation of telomerase activity[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | Endogenous Ceramides (generated in response to bacterial sphingomyelinase overexpression or daunorubicin treatment) inhibits mRNA synthesis of telomerase reverse transcriptase and telomerase activity via inactivation of c-Myc transcription factor in the A549 human lung adenocarcinoma cell line[1]. The sustained generation of long chain endogenous ceramide requires the biochemical recycling of the sphingosine backbone of C6-ceramide, which involves deacylation and reacylation of ceramide for the generation of endogenous long chain ceramide (mainly C16:0- and C24:1-Ceramides), most likely by CoA-dependent ceramide synthase, which is inhibited by fumonisin B1. In A549 cells the generation of long chain endogenous ceramide mediates the effects of exogenous C6-ceramide on growth inhibition, cell cycle arrest, and the modulation of telomerase activity[1]. |
| References |
| Molecular Formula | C24H47NO3 |
|---|---|
| Molecular Weight | 397.63488 |
| Storage condition | -20°C |
| Hazard Codes | Xi |
|---|
| ceramide 1 |
| ceramide 1 a |
| caproyl sphingosine |
| EINECS 309-560-3 |
| ceramide 5 |
| ceramide 6 ii |
| ceramide 4 |
| ceramide 3 |
| ceramide 2 |