TI17
Modify Date: 2025-10-12 11:50:19
TI17 structure
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Common Name | TI17 | ||
|---|---|---|---|---|
| CAS Number | 1005178-02-8 | Molecular Weight | 374.43 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H22N2O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TI17TI17 is an inhibitor of the thyroid hormone receptor-interacting protein Trip13 and has anticancer activity. TI17 effectively inhibits multiple myeloma (MM) cell proliferation and induces cell cycle arrest and apoptosis. Trip13 is an AAA-ATPase that mediates double-strand break (DSB) repair; TI17 inhibits Trip13 function and increases DNA damage[1]. |
| Name | TI17 |
|---|
| Description | TI17 is an inhibitor of the thyroid hormone receptor-interacting protein Trip13 and has anticancer activity. TI17 effectively inhibits multiple myeloma (MM) cell proliferation and induces cell cycle arrest and apoptosis. Trip13 is an AAA-ATPase that mediates double-strand break (DSB) repair; TI17 inhibits Trip13 function and increases DNA damage[1]. |
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| Related Catalog | |
| Target |
Thyroid hormone receptor interacting protein 13 (Trip13)[1] |
| References |
| Molecular Formula | C23H22N2O3 |
|---|---|
| Molecular Weight | 374.43 |