(+/-)-2-HYDROXYTRIDECANOICACID

Modify Date: 2024-01-03 18:35:42

(+/-)-2-HYDROXYTRIDECANOICACID Structure
(+/-)-2-HYDROXYTRIDECANOICACID structure
Common Name (+/-)-2-HYDROXYTRIDECANOICACID
CAS Number 100828-16-8 Molecular Weight 252.20
Density 1.408g/cm3 Boiling Point 546.7ºC at 760mmHg
Molecular Formula C8H17N2O5P Melting Point N/A
MSDS Chinese USA Flash Point 284.4ºC
Symbol GHS07
GHS07
Signal Word Warning

 Use of (+/-)-2-HYDROXYTRIDECANOICACID


(RS)-CPP ((±)-CPP) is a potent and selective NMDA antagonist. (RS)-CPP inhibits central neuron responses, and has anticonvulsant activity[1].

 Names

Name (RS)-3-(2-Carboxypiperazin-4-yl)-propyl-1-phosphonicacid
Synonym More Synonyms

 (+/-)-2-HYDROXYTRIDECANOICACID Biological Activity

Description (RS)-CPP ((±)-CPP) is a potent and selective NMDA antagonist. (RS)-CPP inhibits central neuron responses, and has anticonvulsant activity[1].
Related Catalog
References

[1]. J Davies, et al. CPP, a new potent and selective NMDA antagonist. Depression of central neuron responses, affinity for [3H]D-AP5 binding sites on brain membranes and anticonvulsant activity. Brain Res. 1986 Sep 10;382(1):169-73.  

 Chemical & Physical Properties

Density 1.408g/cm3
Boiling Point 546.7ºC at 760mmHg
Molecular Formula C8H17N2O5P
Molecular Weight 252.20
Flash Point 284.4ºC
Exact Mass 252.08800
PSA 119.91000
Vapour Pressure 2.14E-13mmHg at 25°C
Index of Refraction 1.53

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 36/37/38
Safety Phrases 22-26-36
RIDADR NONH for all modes of transport

 Synthetic Route

~76%

(+/-)-2-HYDROXYTRIDECANOICACID Structure

(+/-)-2-HYDROXY...

CAS#:100828-16-8

Literature: Demaine; Smith Synthesis, 1992 , # 11 p. 1065 - 1067

~%

(+/-)-2-HYDROXYTRIDECANOICACID Structure

(+/-)-2-HYDROXY...

CAS#:100828-16-8

Literature: British Technology Group Limited Patent: US5399693 A1, 1995 ;

~%

(+/-)-2-HYDROXYTRIDECANOICACID Structure

(+/-)-2-HYDROXY...

CAS#:100828-16-8

Literature: Demaine; Smith Synthesis, 1992 , # 11 p. 1065 - 1067

~75%

(+/-)-2-HYDROXYTRIDECANOICACID Structure

(+/-)-2-HYDROXY...

CAS#:100828-16-8

Literature: Demaine; Smith Synthesis, 1992 , # 11 p. 1065 - 1067

~%

(+/-)-2-HYDROXYTRIDECANOICACID Structure

(+/-)-2-HYDROXY...

CAS#:100828-16-8

Literature: Pevarello, P.; Scappi, G.; Varasi, M. Organic Preparations and Procedures International, 1994 , vol. 26, # 3 p. 366 - 370

~%

(+/-)-2-HYDROXYTRIDECANOICACID Structure

(+/-)-2-HYDROXY...

CAS#:100828-16-8

Literature: Demaine; Smith Synthesis, 1992 , # 11 p. 1065 - 1067

~%

(+/-)-2-HYDROXYTRIDECANOICACID Structure

(+/-)-2-HYDROXY...

CAS#:100828-16-8

Literature: Pevarello, P.; Scappi, G.; Varasi, M. Organic Preparations and Procedures International, 1994 , vol. 26, # 3 p. 366 - 370

 Articles250

More Articles
High-content screening imaging and real-time cellular impedance monitoring for the assessment of chemical's bio-activation with regards hepatotoxicity.

Toxicol. In Vitro 29 , 1916-31, (2015)

Testing hepatotoxicity is a crucial step in the development and toxicological assessment of drugs and chemicals. Bio-activation can lead to the formation of metabolites which may present toxicity for ...

Higher vulnerability and stress sensitivity of neuronal precursor cells carrying an alpha-synuclein gene triplication.

PLoS ONE 9(11) , e112413, (2014)

Parkinson disease (PD) is a multi-factorial neurodegenerative disorder with loss of dopaminergic neurons in the substantia nigra and characteristic intracellular inclusions, called Lewy bodies. Geneti...

Regulation of AMPA receptor phosphorylation by the neuropeptide PACAP38.

Proc. Natl. Acad. Sci. U. S. A. 112 , 6712-7, (2015)

Dynamic changes in synaptic strength are thought to be critical for higher brain function such as learning and memory. Alterations in synaptic strength can result from modulation of AMPA receptor (AMP...

 Synonyms

3-2-Cpp
DL-CPP