Kushenol L

Modify Date: 2025-08-26 07:23:55

Kushenol L Structure
Kushenol L structure
Common Name Kushenol L
CAS Number 101236-50-4 Molecular Weight 440.486
Density 1.3±0.1 g/cm3 Boiling Point 715.7±60.0 °C at 760 mmHg
Molecular Formula C25H28O7 Melting Point N/A
MSDS N/A Flash Point 244.7±26.4 °C

 Use of Kushenol L


Kushenol L is one of the main components of EtOA cextracts from Kushen, a traditional medicinal herb derived from the dried roots of Sophora flavescens Ait. Kushenol L is a flavonoid and plays an important role in anti-diabeticeffects[1].

 Names

Name Kushenol L
Synonym More Synonyms

 Kushenol L Biological Activity

Description Kushenol L is one of the main components of EtOA cextracts from Kushen, a traditional medicinal herb derived from the dried roots of Sophora flavescens Ait. Kushenol L is a flavonoid and plays an important role in anti-diabeticeffects[1].
Related Catalog
In Vivo Kushenol L (1 mg/kg; oral) has a T1/2 of 2.26 hours, a Cmax of 24.17 μg/L and an AUC of 54035 μg/h•L in adult male Sprague-Dawley rats weighing 300 g[1].
References

[1]. Lei Chen, et al. An accurate and reproducible method for simultaneous determination of four flavonoids in EtOAc extracts from Sophora flavescens Ait. in rat plasma based on UHPLC Q-Exactive Mass spectrometry: Application to a pharmacokinetics study. Biomed Chromatogr. 2019 Mar;33(3):e4447.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 715.7±60.0 °C at 760 mmHg
Molecular Formula C25H28O7
Molecular Weight 440.486
Flash Point 244.7±26.4 °C
Exact Mass 440.183502
PSA 127.45000
LogP 5.88
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.650
InChIKey GKENRJIRKFSNED-UKILVPOCSA-N
SMILES CC(C)=CCc1c(O)c(CC=C(C)C)c2c(c1O)C(=O)C(O)C(c1ccc(O)cc1O)O2

 Safety Information

Hazard Codes Xi

 Synonyms

(2R,3R)-2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-6,8-bis(3-methyl-2-buten-1-yl)-2,3-dihydro-4H-chromen-4-one
(2R,3R)-2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxy-6,8-bis(3-methylbut-2-en-1-yl)-2,3-dihydro-4H-chromen-4-one
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