L-750667

Modify Date: 2024-01-10 18:02:00

L-750667 Structure
L-750667 structure
Common Name L-750667
CAS Number 1021868-80-3 Molecular Weight 527.65800
Density N/A Boiling Point N/A
Molecular Formula C18H22Cl3IN4 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

 Use of L-750667


L-750,667 TriHydrochloride is a selective D4 dopamine receptor antagonist.

 Names

Name L-750,667 trihydrochloride
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C18H22Cl3IN4
Molecular Weight 527.65800
Exact Mass 525.99500
PSA 35.16000
LogP 5.89860

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H315-H319-H335
Precautionary Statements P301 + P312 + P330-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Articles6

More Articles
Nonconserved residues in the second transmembrane-spanning domain of the D(4) dopamine receptor are molecular determinants of D(4)-selective pharmacology.

Mol. Pharmacol. 57 , 144-152, (2000)

The molecular determinants that govern selective ligand binding to the rat D(4) dopamine receptor were investigated by substituting D(2) dopamine receptor sequences into a D(4) dopamine receptor backg...

3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor.

J. Med. Chem. 39 , 1941, (1996)

Adrenomedullin enhances angiogenic potency of bone marrow transplantation in a rat model of hindlimb ischemia.

Circulation 111 , 356-62, (2005)

Previous studies have shown that adrenomedullin (AM) inhibits vascular endothelial cell apoptosis and induces angiogenesis. We investigated whether AM enhances bone marrow cell-induced angiogenesis.Im...

 Synonyms

3-[[4-(4-iodophenyl)piperazin-1-yl]methyl]-1H-pyrrolo[2,3-b]pyridine,trihydrochloride