PP5-IN-1

Modify Date: 2024-02-01 13:50:20

PP5-IN-1 Structure
PP5-IN-1 structure
Common Name PP5-IN-1
CAS Number 1022417-69-1 Molecular Weight 342.41
Density N/A Boiling Point N/A
Molecular Formula C18H18N2O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PP5-IN-1


PP5-IN-1 (Compound P053) is a competitive inhibitor of Serine/threonine protein phosphatase-5 (PP5) that binds to its catalytic domain and causes apoptosis in renal cancer[1].

 Names

Name PP5-IN-1

 PP5-IN-1 Biological Activity

Description PP5-IN-1 (Compound P053) is a competitive inhibitor of Serine/threonine protein phosphatase-5 (PP5) that binds to its catalytic domain and causes apoptosis in renal cancer[1].
Related Catalog
References

[1]. Elham F Ahanin, et al. Catalytic inhibitor of Protein Phosphatase 5 activates the extrinsic apoptotic pathway by disrupting complex II in kidney cancer. Cell Chem Biol. 2023 Oct 19;30(10):1223-1234.e12.  

 Chemical & Physical Properties

Molecular Formula C18H18N2O3S
Molecular Weight 342.41
InChIKey QDUOZMMIRWIMGB-UHFFFAOYSA-N
SMILES Cc1noc(C)c1S(=O)(=O)Nc1ccc(Cc2ccccc2)cc1
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