7-Octynoic acid

Modify Date: 2025-08-26 08:43:19

7-Octynoic acid Structure
7-Octynoic acid structure
Common Name 7-Octynoic acid
CAS Number 10297-09-3 Molecular Weight 140.18000
Density N/A Boiling Point N/A
Molecular Formula C8H12O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 7-Octynoic acid


7-Octynoic acid (compound 42) is a PROTAC linker and can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

 Names

Name oct-7-ynoic acid
Synonym More Synonyms

 7-Octynoic acid Biological Activity

Description 7-Octynoic acid (compound 42) is a PROTAC linker and can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
References

[1]. Bai L, et al. A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo. Cancer Cell. 2019 Nov 11;36(5):498-511.e17.

 Chemical & Physical Properties

Molecular Formula C8H12O2
Molecular Weight 140.18000
Exact Mass 140.08400
PSA 37.30000
LogP 1.65470
Storage condition 2-8℃

 Safety Information

HS Code 2916190090

 Synthetic Route

 Customs

HS Code 2916190090
Summary 2916190090 unsaturated acyclic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:6.5%。general tariff:30.0%

 Synonyms

7-Octynoic acid
Oct-7-insaeure
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here


Get all suppliers and price by the below link:

7-Octynoic acid suppliers

7-Octynoic acid price

Related Compounds: More...
7-octynoic acid ethyl ester
108545-39-7
7-Octynoic acid methyl ester
18458-50-9
(2S)-2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-7-octynoic acid
1097192-06-7
methyl 7-iodooct-2-ynoate
144226-58-4
methyl 4-phenyloct-2-ynoate
62360-11-6
methyl 4-methyl-4-phenyloct-2-ynoate
62360-15-0
6-Octynoicacid,2-amino-,(2R)-(9CI)
375859-47-5
6-Octynoicacid,2-amino-,(2S)-(9CI)
375859-46-4
3-hydroxy-4-methyl-2-(methylamino)oct-6-ynoic acid
124562-10-3
[2-(4-ethoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl 1-(4-bromo-3-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylate
1223794-96-4
(2-(4-isopropoxyphenyl)-5-methyloxazol-4-yl)methyl 1-(4-bromo-3-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylate
1223945-15-0
2-[3-{4-[2-(cyclohexylamino)-2-oxoethyl]phenyl}-2,4-dioxo-3,4-dihydroquinazolin-1(2H)-yl]-N-cyclopentylacetamide
1223769-40-1
[2-(2,3-dimethoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl 1-(4-bromo-3-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylate
1223972-05-1
[2-(4-ethoxy-3-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl 1-(4-bromo-3-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylate
1223835-92-4
[2-(2-ethoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl 1-(4-bromo-3-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxylate
1223850-68-7
2-((7-(3-methoxyphenyl)-8-oxo-7,8-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-3-yl)thio)-N-(p-tolyl)acetamide
1185056-10-3
Tert-butyl 2-((2-(benzo[d][1,3]dioxol-5-ylamino)-2-oxoethyl)thio)-3-(3-methoxyphenyl)-1,4,8-triazaspiro[4.5]deca-1,3-diene-8-carboxylate
1223921-17-2
Tert-butyl 2-((2-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)amino)-2-oxoethyl)thio)-3-(3-methoxyphenyl)-1,4,8-triazaspiro[4.5]deca-1,3-diene-8-carboxylate
1224009-47-5
methyl 2-(2-(4-methylpiperidin-1-yl)-2-oxoethyl)-4-phenyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide
1189973-35-0