2-(5-bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene

Modify Date: 2025-08-21 19:05:13

2-(5-bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene Structure
2-(5-bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene structure
Common Name 2-(5-bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene
CAS Number 1030825-20-7 Molecular Weight 361.271
Density 1.4±0.1 g/cm3 Boiling Point 438.3±40.0 °C at 760 mmHg
Molecular Formula C18H14BrFS Melting Point 103 °C
MSDS N/A Flash Point 218.9±27.3 °C

 Names

Name 2-[(5-bromo-2-methylphenyl)methyl]-5-(4-fluorophenyl)thiophene
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 438.3±40.0 °C at 760 mmHg
Melting Point 103 °C
Molecular Formula C18H14BrFS
Molecular Weight 361.271
Flash Point 218.9±27.3 °C
Exact Mass 359.998352
PSA 28.24000
LogP 6.93
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.617

 Safety Information

Hazard Codes Xi
HS Code 2934999090

 Synthetic Route

~76%

2-(5-bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene Structure

2-(5-bromo-2-me...

CAS#:1030825-20-7

Literature: Nomura, Sumihiro; Sakamaki, Shigeki; Hongu, Mitsuya; Kawanishi, Eiji; Koga, Yuichi; Sakamoto, Toshiaki; Yamamoto, Yasuo; Ueta, Kiichiro; Kimata, Hirotaka; Nakayama, Keiko; Tsuda-Tsukimoto, Minoru Journal of Medicinal Chemistry, 2010 , vol. 53, # 17 p. 6355 - 6360

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2-(5-bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene Structure

2-(5-bromo-2-me...

CAS#:1030825-20-7

Literature: WO2012/160218 A1, ; WO 2012/160218 A1

~%

2-(5-bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene Structure

2-(5-bromo-2-me...

CAS#:1030825-20-7

Literature: WO2012/160218 A1, ; WO 2012/160218 A1

~%

2-(5-bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene Structure

2-(5-bromo-2-me...

CAS#:1030825-20-7

Literature: WO2012/160218 A1, ; WO 2012/160218 A1

~%

2-(5-bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene Structure

2-(5-bromo-2-me...

CAS#:1030825-20-7

Literature: WO2012/160218 A1, ; WO 2012/160218 A1

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

2-(5-Bromo-2-methylbenzyl)-5-(4-fluorophenyl)thiophene
Canagliflozin intermediate
Thiophene, 2-[(5-bromo-2-methylphenyl)methyl]-5-(4-fluorophenyl)-
2-((5-bromo-2-methylphenyl)methyl)-5-(4-fluorophenyl)thiophene
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