TYR-GLY-ALA-VAL-VAL-ASN-ASP-LEU

Modify Date: 2025-08-27 16:45:50

TYR-GLY-ALA-VAL-VAL-ASN-ASP-LEU Structure
TYR-GLY-ALA-VAL-VAL-ASN-ASP-LEU structure
Common Name TYR-GLY-ALA-VAL-VAL-ASN-ASP-LEU
CAS Number 103424-74-4 Molecular Weight 849.92800
Density N/A Boiling Point N/A
Molecular Formula C38H59N9O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TYR-GLY-ALA-VAL-VAL-ASN-ASP-LEU


Herpes virus inhibitor 2 is a herpes virus inhibitor and disrupts herpes virus ribonucleotide reductase quaternary structure. Herpes virus inhibitor 2 inhibits viral replication[1][2].

 Names

Name 2-[[2-[[4-amino-2-[[2-[[2-[2-[[2-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]propanoylamino]-3-methylbutanoyl]amino]-3-methylbutanoyl]amino]-4-oxobutanoyl]amino]-3-carboxypropanoyl]amino]-4-methylpentanoic acid
Synonym More Synonyms

 TYR-GLY-ALA-VAL-VAL-ASN-ASP-LEU Biological Activity

Description Herpes virus inhibitor 2 is a herpes virus inhibitor and disrupts herpes virus ribonucleotide reductase quaternary structure. Herpes virus inhibitor 2 inhibits viral replication[1][2].
Related Catalog
References

[1]. Dutia BM, et, al. Specific inhibition of herpesvirus ribonucleotide reductase by synthetic peptides. Nature. 1986 May 22-28;321(6068):439-41.   

[2]. Gaudreau P, et, al. Structure-activity studies on synthetic peptides inhibiting herpes simplex virus ribonucleotide reductase. J Biol Chem. 1987 Sep 15;262(26):12413-6.   

 Chemical & Physical Properties

Molecular Formula C38H59N9O13
Molecular Weight 849.92800
Exact Mass 849.42300
PSA 393.06000
LogP 4.83180
InChIKey URCVABGAANCWFR-UHFFFAOYSA-N
SMILES CC(C)CC(NC(=O)C(CC(=O)O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(NC(=O)C(C)NC(=O)CNC(=O)C(N)Cc1ccc(O)cc1)C(C)C)C(C)C)C(=O)O

 Synthetic Route

~%

Detail
Literature: Gaudreau, Pierrette; Paradis, Helene; Langelier, Yves; Brazeau, Paul Journal of Medicinal Chemistry, 1990 , vol. 33, # 2 p. 723 - 730

 Synonyms

tyr-gly-ala-val-val-asn-asp-leu
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