(Tyr4)-Bombesin

Modify Date: 2024-01-02 18:04:09

(Tyr4)-Bombesin structure	Common Name	(Tyr4)-Bombesin
	CAS Number	67338-70-9	Molecular Weight	1669.864
	Density	1.5±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₇₄H₁₀₈N₂₄O₁₉S	Melting Point	N/A
	MSDS	USA	Flash Point	N/A

Use of (Tyr4)-Bombesin

[Tyr4]-Bombesin is a Bombesin analogue, is a ligand of gastrin-releasing peptide receptor (GRPR)[1].

Name	pyr-gln-arg-tyr-gly-asn-gln-trp-ala-val-gly-his-leu-met-nh2
Synonym	More Synonyms

Description	[Tyr4]-Bombesin is a Bombesin analogue, is a ligand of gastrin-releasing peptide receptor (GRPR)[1].
Related Catalog	Research Areas >> Metabolic Disease Signaling Pathways >> GPCR/G Protein >> Bombesin Receptor
References	[1]. Joseph Lau, et al. Effect of Radiometal on Binding Affinity and Biodistribution of ProBOMB1, a Novel Bombesin Derivative. Journal of Nuclear Medicine May 2019, 60 (supplement 1) 1013.

Density	1.5±0.1 g/cm3
Molecular Formula	C₇₄H₁₀₈N₂₄O₁₉S
Molecular Weight	1669.864
Exact Mass	1668.794312
PSA	731.66000
LogP	-4.93
Index of Refraction	1.693
Storage condition	-20°C

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3.0

Bombesin receptors in distinct tissue compartments of human pancreatic diseases.

Lab. Invest. 80 , 1807-1817, (2000)

Overexpression of receptors for regulatory peptides in various human diseases is reportedly of clinical interest. Among these peptides, bombesin and gastrin-releasing peptide (GRP) have been shown to ...

Modulation of bombesin-induced phosphatidylinositol hydrolysis in a small-cell lung-cancer cell line.

Biochem. J. 255 , 403-410, (1988)

Bombesin is an amphibian tetradecapeptide whose mammalian homologue, gastrin-releasing peptide (GRP), is produced by many small-cell lung-cancer (SCLC) cells, and which can function in an autocrine gr...

Investigation of molecular structure of bombesin and its modified analogues nonadsorbed and adsorbed on electrochemically roughened silver surface.

Biopolymers 89 , 506-521, (2008)

This work describes the molecular structure of bombesin (BN) and its analogs on the basis of the absorption infrared and Raman results described below. In these analogues is replaced one ([D-Phe12]BN,...

PYROGLU-GLN-ARG-TYR-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET NH2

L-Methioninamide, 5-oxo-L-prolyl-L-glutaminyl-L-arginyl-L-tyrosylglycyl-L-asparaginyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-L-leucyl-

GLP-GLN-ARG-TYR-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2

5-Oxo-L-prolyl-L-glutaminyl-L-arginyl-L-tyrosylglycyl-L-asparaginyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-L-leucyl-L-methioninamide

PGLU-GLN-ARG-TYR-GLY-ASN-GLN-TRP-ALA-VAL-GLY-HIS-LEU-MET-NH2

5-Oxo-L-Pro-L-Gln-L-Arg-Tyr-Gly-L-Asn-L-Gln-L-Trp-L-Ala-L-Val-Gly-L-His-L-Leu-L-Met-NH2

PYR-QRYGNQWAVGHLM-NH2

bombesin-4-L-tyrosine