(6R)-FR054

Modify Date: 2025-08-26 16:17:28

(6R)-FR054 Structure
(6R)-FR054 structure
 Common Name (6R)-FR054
CAS Number 10378-06-0 Molecular Weight 329.30300
Density N/A Boiling Point N/A
Molecular Formula C14H19NO8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (6R)-FR054


(6R)-FR054 is an active isomer of FR054. FR054 is an inhibitor of the HBP enzyme PGM3, with a remarkable anti-breast cancer effect. FR054induces endoplasmic reticulum (ER) stress and a ROS-dependent apoptosis[1].

 Names

Name methyl (3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyrano)-[2,1-D]-Δ2-oxazolidine
Synonym More Synonyms

 (6R)-FR054 Biological Activity

Description (6R)-FR054 is an active isomer of FR054. FR054 is an inhibitor of the HBP enzyme PGM3, with a remarkable anti-breast cancer effect. FR054induces endoplasmic reticulum (ER) stress and a ROS-dependent apoptosis[1].
Related Catalog
References

[1]. Francesca Ricciardiello, et al. Inhibition of the Hexosamine Biosynthetic Pathway by Targeting PGM3 Causes Breast Cancer Growth Arrest and Apoptosis. Cell Death Dis. 2018 Mar 7;9(3):377.

 Chemical & Physical Properties

Molecular Formula C14H19NO8
Molecular Weight 329.30300
Exact Mass 329.11100
PSA 109.72000
Storage condition 2-8°C

 Synonyms

4',5'-dihydro-2'-methoxyoxazolo[5',4':1,2]-3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyranoside
2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyrano)-<2,1-d>-2-oxazoline
4',5'-dihydro-2'-methyloxazolo[5',4':1,2]-3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyranose
2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyranoso)-[2,1-d]-2-oxazoline
2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyrano)-[2',1':4,5]-2-oxazoline
2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyranosido)-[2,1-d]-2-oxazoline
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Chemsrc provides (6R)-FR054(CAS#:10378-06-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of (6R)-FR054 are included as well.>> amp version: (6R)-FR054

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