(6R)-FR054

Modify Date: 2024-01-10 12:30:08

(6R)-FR054 structure	Common Name	(6R)-FR054
	CAS Number	10378-06-0	Molecular Weight	329.30300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₁₉NO₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of (6R)-FR054

(6R)-FR054 is an active isomer of FR054. FR054 is an inhibitor of the HBP enzyme PGM3, with a remarkable anti-breast cancer effect. FR054induces endoplasmic reticulum (ER) stress and a ROS-dependent apoptosis[1].

Name	methyl (3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyrano)-[2,1-D]-Δ2-oxazolidine
Synonym	More Synonyms

Description	(6R)-FR054 is an active isomer of FR054. FR054 is an inhibitor of the HBP enzyme PGM3, with a remarkable anti-breast cancer effect. FR054induces endoplasmic reticulum (ER) stress and a ROS-dependent apoptosis[1].
Related Catalog	Signaling Pathways >> Apoptosis >> Apoptosis Research Areas >> Cancer
References	[1]. Francesca Ricciardiello, et al. Inhibition of the Hexosamine Biosynthetic Pathway by Targeting PGM3 Causes Breast Cancer Growth Arrest and Apoptosis. Cell Death Dis. 2018 Mar 7;9(3):377.

Molecular Formula	C₁₄H₁₉NO₈
Molecular Weight	329.30300
Exact Mass	329.11100
PSA	109.72000
Storage condition	2-8°C

Precursor 0
DownStream 9
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4',5'-dihydro-2'-methoxyoxazolo[5',4':1,2]-3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyranoside

2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyrano)-<2,1-d>-2-oxazoline

4',5'-dihydro-2'-methyloxazolo[5',4':1,2]-3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyranose

2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyranoso)-[2,1-d]-2-oxazoline

2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyrano)-[2',1':4,5]-2-oxazoline

2-methyl-(3,4,6-tri-O-acetyl-1,2-dideoxy-α-D-glucopyranosido)-[2,1-d]-2-oxazoline

DC Chemicals Limited
China
Product Name: FR054
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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