Maxacalcitol
Modify Date: 2024-01-07 09:03:39
Maxacalcitol structure
|
Common Name | Maxacalcitol | ||
|---|---|---|---|---|
| CAS Number | 103909-75-7 | Molecular Weight | 418.609 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 581.4±50.0 °C at 760 mmHg | |
| Molecular Formula | C26H42O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 305.4±30.1 °C | |
Use of MaxacalcitolMaxacalcitol (22-Oxacalcitriol) is non-calcemic vitamin D3 analog and ligand of VDR-like receptors. IC50 value:Target: Maxacalcitol (22-Oxacalcitriol)suppresses parathyroid hormone (PTH) mRNA expression in vitro and in vivo. Maxacalcitol exhibits similar effects to calcitriol in osteoblast-like cells. Maxacalcitol(22-Oxacalcitriol) inhibits tumor growth of osteosarcoma in vitro in combination with all-trans retinoic acid. |
| Name | (1R,3S,5Z)-5-[(2E)-2-[(1S,3aS,7aS)-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol |
|---|---|
| Synonym | More Synonyms |
| Description | Maxacalcitol (22-Oxacalcitriol) is non-calcemic vitamin D3 analog and ligand of VDR-like receptors. IC50 value:Target: Maxacalcitol (22-Oxacalcitriol)suppresses parathyroid hormone (PTH) mRNA expression in vitro and in vivo. Maxacalcitol exhibits similar effects to calcitriol in osteoblast-like cells. Maxacalcitol(22-Oxacalcitriol) inhibits tumor growth of osteosarcoma in vitro in combination with all-trans retinoic acid. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 581.4±50.0 °C at 760 mmHg |
| Molecular Formula | C26H42O4 |
| Molecular Weight | 418.609 |
| Flash Point | 305.4±30.1 °C |
| Exact Mass | 418.308319 |
| PSA | 69.92000 |
| LogP | 4.38 |
| Vapour Pressure | 0.0±3.7 mmHg at 25°C |
| Index of Refraction | 1.549 |
| Storage condition | 2-8℃ |
CAS#:917-54-4
CAS#:413571-27-4
CAS#:20998-18-9![1α,3β-bis[(tert-butyldimethylsilyl)oxy]androst-5-en-17-one Structure](https://www.chemsrc.com/caspic/059/111594-61-7.png)
CAS#:111594-61-7![tert-butyl-[(1R,3S,5Z)-3-[tert-butyl(dimethyl)silyl]oxy-5-(2-diphenylphosphorylethylidene)-4-methylidenecyclohexyl]oxy-dimethylsilane Structure](https://www.chemsrc.com/caspic/143/81522-68-1.png)
CAS#:81522-68-1
CAS#:192573-35-6
CAS#:413571-28-5| Oxarol |
| (1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol |
| (1S,3R,5Z,7E,20S)-20-(3-hydroxy-3-methylbutoxy)-9,10-secopregna-5,7,10-triene-1,3-diol |
| 1α,25-Dihydroxy-22-oxavitamin D3 |
| MC 1275 |
| Maxacalcitol |
| (1S,3R,5Z,7E,9ξ)-20-(3-hydroxy-3-methylbutoxy)-9,10-secopregna-5,7,10-triene-1,3-diol |
| 1,25-dihydroxy-22-oxavitamin D3 |
| 22-Oxacalcitriol |
| (1S,3R,5Z,7E,9ξ,20S)-20-(3-Hydroxy-3-methylbutoxy)-9,10-secopregna-5,7,10-triene-1,3-diol |
| 1,3-cyclohexanediol, 4-methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)- |
| Prezios |
| (1S-(1a(R*),3ab,4E(1S*,3R*,5Z),7aa))-4-Methylene-5-(2-(octahydro-1-(1-(3-hydroxy-3-methylbutoxy)ethyl)-7a-methyl-4H-inden-4-ylidene)ethylidene)-1,3-cyclohexanediol |
| 22-Oxa-1,25-dihydroxyvitamin D3 |
| 1alpha,25-Dihydroxy-22-oxavitamin D3 |
| 1R,25-dihydroxy-22-oxavitamin D3 |
| 1a,25-Dihydroxy-22-oxavitamin D3 |
| 1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)- |