马沙骨化醇

更新时间：2024-01-07 09:03:39

马沙骨化醇结构式	常用名	马沙骨化醇	英文名	Maxacalcitol
	CAS号	103909-75-7	分子量	418.609
	密度	1.1±0.1 g/cm3	沸点	581.4±50.0 °C at 760 mmHg
	分子式	C₂₆H₄₂O₄	熔点	N/A
	MSDS	N/A	闪点	305.4±30.1 °C

马沙骨化醇用途

Maxacalcitol (22-Oxacalcitriol)是维生素D3类似物。

中文名	马沙骨化醇
英文名	(1R,3S,5Z)-5-[(2E)-2-[(1S,3aS,7aS)-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
英文别名	更多

描述	Maxacalcitol (22-Oxacalcitriol)是维生素D3类似物。
相关类别	信号通路 >> 维生素 D 相关 >> VD/VDR 研究领域 >> 代谢疾病
参考文献	[1]. Barroga, et al. Inhibitory effects of 22-oxa-calcitriol and all-trans retinoic acid on the growth of a canine osteosarcoma derived cell-line in vivo and its pulmonary metastasis in vivo. Res.Vet.Sci. (2000)68 79. [2]. Monier-Faugere, et al. 22-Oxacalcitriol suppresses secondary hyperparathyroidism without inducing low bone turnover in dogs with renal failure. Kidney Int. (1999)55 821. [3]. Inoue K, et al. Maxacalcitol ameliorates tubulointerstitial fibrosis in obstructed kidneys by recruiting PPM1A/VDR complex to pSmad3.Lab Invest. 2012 Aug 27. [4]. Karashima T, et al. Successful Treatment of Bowen's Disease with Topical Maxacalcitol.Acta Derm Venereol. 2012 Jan 26.

描述

Maxacalcitol (22-Oxacalcitriol)是维生素D3类似物。

相关类别

信号通路 >> 维生素 D 相关 >> VD/VDR

研究领域 >> 代谢疾病

参考文献

[1]. Barroga, et al. Inhibitory effects of 22-oxa-calcitriol and all-trans retinoic acid on the growth of a canine osteosarcoma derived cell-line in vivo and its pulmonary metastasis in vivo. Res.Vet.Sci. (2000)68 79.

[2]. Monier-Faugere, et al. 22-Oxacalcitriol suppresses secondary hyperparathyroidism without inducing low bone turnover in dogs with renal failure. Kidney Int. (1999)55 821.

[3]. Inoue K, et al. Maxacalcitol ameliorates tubulointerstitial fibrosis in obstructed kidneys by recruiting PPM1A/VDR complex to pSmad3.Lab Invest. 2012 Aug 27.

[4]. Karashima T, et al. Successful Treatment of Bowen's Disease with Topical Maxacalcitol.Acta Derm Venereol. 2012 Jan 26.

密度	1.1±0.1 g/cm3
沸点	581.4±50.0 °C at 760 mmHg
分子式	C₂₆H₄₂O₄
分子量	418.609
闪点	305.4±30.1 °C
精确质量	418.308319
PSA	69.92000
LogP	4.38
蒸汽压	0.0±3.7 mmHg at 25°C
折射率	1.549
储存条件	2-8℃

马沙骨化醇上游产品 7
CAS号917-54-4 甲基锂 CAS号413571-27-4 3-((S)-1-((1S,3... CAS号20998-18-9 1-hydroxydehydr... CAS号111594-61-7 1α,3β-bis[(tert...
CAS号81522-68-1 [3S-(1Z,3a,5b)]... CAS号192573-35-6 ethyl 3-((S)-1-... CAS号413571-28-5 ethyl 3-((S)-1-...
马沙骨化醇下游产品 0

Oxarol

(1R,3S,5Z)-4-Methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-1,3-cyclohexanediol

(1S,3R,5Z,7E,20S)-20-(3-hydroxy-3-methylbutoxy)-9,10-secopregna-5,7,10-triene-1,3-diol

1α,25-Dihydroxy-22-oxavitamin D3

MC 1275

Maxacalcitol

(1S,3R,5Z,7E,9ξ)-20-(3-hydroxy-3-methylbutoxy)-9,10-secopregna-5,7,10-triene-1,3-diol

1,25-dihydroxy-22-oxavitamin D3

22-Oxacalcitriol

(1S,3R,5Z,7E,9ξ,20S)-20-(3-Hydroxy-3-methylbutoxy)-9,10-secopregna-5,7,10-triene-1,3-diol

1,3-cyclohexanediol, 4-methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)-

Prezios

(1S-(1a(R*),3ab,4E(1S*,3R*,5Z),7aa))-4-Methylene-5-(2-(octahydro-1-(1-(3-hydroxy-3-methylbutoxy)ethyl)-7a-methyl-4H-inden-4-ylidene)ethylidene)-1,3-cyclohexanediol

22-Oxa-1,25-dihydroxyvitamin D3

1alpha,25-Dihydroxy-22-oxavitamin D3

1R,25-dihydroxy-22-oxavitamin D3

1a,25-Dihydroxy-22-oxavitamin D3

1,3-Cyclohexanediol, 4-methylene-5-[(2E)-2-[(1S,3aS,7aS)-octahydro-1-[(1S)-1-(3-hydroxy-3-methylbutoxy)ethyl]-7a-methyl-4H-inden-4-ylidene]ethylidene]-, (1R,3S,5Z)-