Budesonide impurity C

Modify Date: 2024-01-02 18:52:51

Budesonide impurity C structure	Common Name	Budesonide impurity C
	CAS Number	1040085-99-1	Molecular Weight	430.534
	Density	1.3±0.1 g/cm3	Boiling Point	607.0±55.0 °C at 760 mmHg
	Molecular Formula	C₂₅H₃₄O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	204.6±25.0 °C

Use of Budesonide impurity C

Budesonide impurity C is an impurity of Budesonide. Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist[1][2].

Name	(4aR,4bS,5S,6aS,7aR,10aR,11aS,11bS)-5-Hydroxy-7a-(hydroxymethyl)-4a,6a-dimethyl-9-propyl-4b,6,6a,7a,10a,11,11a,11b,12,13-decahydrochryseno[2,3-d][1,3]dioxole-2,7(4aH,5H)-dione
Synonym	More Synonyms

Description	Budesonide impurity C is an impurity of Budesonide. Budesonide, an inhaled glucocortical steroid, is an orally active glucocorticoid receptor agonist[1][2].
Related Catalog	Research Areas >> Cancer Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Glucocorticoid Receptor
In Vitro	Budesonide is selective for human glucocorticoid receptor (hGR; EC50=45.7 pM) over mineralocorticoid receptors (EC50=7,620 pM) in CV-1 cells[1]. Budesonide (30 min prior to LPS) suppresses the activation of the NLRP3 inflammasome by LPS (100 ng/mL) plus ATP (5 mM) in macrophages (RAW 264.7 cells)[2].
References	[1]. Patrizia Ferraboschi, et al. Estimation and Characterisation of Budesonide Tablets Impurities. J Pharm Biomed Anal. 2008 Jul 15;47(3):636-40. [2]. Claudia Grossmann, et al. Transactivation via the Human Glucocorticoid and Mineralocorticoid Receptor by Therapeutically Used Steroids in CV-1 Cells: A Comparison of Their Glucocorticoid and Mineralocorticoid Properties. Eur J Endocrinol. 2004 Sep;151(3):397-406.

Density	1.3±0.1 g/cm3
Boiling Point	607.0±55.0 °C at 760 mmHg
Molecular Formula	C₂₅H₃₄O₆
Molecular Weight	430.534
Flash Point	204.6±25.0 °C
Exact Mass	430.235535
LogP	2.56
Vapour Pressure	0.0±3.9 mmHg at 25°C
Index of Refraction	1.592

(4aR,4bS,5S,6aS,7aR,10aR,11aS,11bS)-5-Hydroxy-7a-(hydroxymethyl)-4a,6a-dimethyl-9-propyl-4b,6,6a,7a,10a,11,11a,11b,12,13-decahydrochryseno[2,3-d][1,3]dioxole-2,7(4aH,5H)-dione

Chryseno[2,3-d][1,3]dioxole-2,7(4aH,5H)-dione, 4b,6,6a,7a,10a,11,11a,11b,12,13-decahydro-5-hydroxy-7a-(hydroxymethyl)-4a,6a-dimethyl-9-propyl-, (4aR,4bS,5S,6aS,7aR,10aR,11aS,11bS)-

Budesonide Impurity 3

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Budesonide impurity C
Price: Negotiable
Purity: 95.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Budesonide impurity C
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 16α,17-[(1RS)-Butylidenebis(oxy)]-11β-hydroxy-17-(hydroxyMethyl)-D-homoandrosta-1,4-diene-3,17a-dione (Mixture of DiastereoMers)
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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