4-Hydroxy-3-nitrophenylacetic acid

Modify Date: 2025-08-23 15:16:19

4-Hydroxy-3-nitrophenylacetic acid Structure
4-Hydroxy-3-nitrophenylacetic acid structure
Common Name 4-Hydroxy-3-nitrophenylacetic acid
CAS Number 10463-20-4 Molecular Weight 197.14500
Density 1.435 g/cm3 Boiling Point 302.9ºC at 760 mmHg
Molecular Formula C8H7NO5 Melting Point 146-148 °C(lit.)
MSDS Chinese USA Flash Point 137ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4-Hydroxy-3-Nitrophenylacetic Acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.435 g/cm3
Boiling Point 302.9ºC at 760 mmHg
Melting Point 146-148 °C(lit.)
Molecular Formula C8H7NO5
Molecular Weight 197.14500
Flash Point 137ºC
Exact Mass 197.03200
PSA 103.35000
LogP 1.45070
Vapour Pressure 5.38E-07mmHg at 25°C
InChIKey QBHBHOSRLDPIHG-UHFFFAOYSA-N
SMILES O=C(O)Cc1ccc(O)c([N+](=O)[O-])c1
Storage condition −20°C

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H315-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2918290000

 Synthetic Route

~74%

4-Hydroxy-3-nitrophenylacetic acid Structure

4-Hydroxy-3-nit...

CAS#:10463-20-4

Literature: Huegel, Helmut M. Synthetic Communications, 1985 , vol. 15, # 12 p. 1075 - 1080

~%

4-Hydroxy-3-nitrophenylacetic acid Structure

4-Hydroxy-3-nit...

CAS#:10463-20-4

Literature: Tetrahedron Letters, , vol. 40, # 38 p. 6933 - 6937

 Customs

HS Code 2918290000
Summary HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

 Articles30

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B cells in T follicular helper cell development and function: separable roles in delivery of ICOS ligand and antigen.

J. Immunol. 192(7) , 3166-79, (2014)

B cells are required for follicular Th (Tfh) cell development, as is the ICOS ligand (ICOS-L); however, the separable contributions of Ag and ICOS-L delivery by cognate B cells to Tfh cell development...

A role for lysosomal-associated protein transmembrane 5 in the negative regulation of surface B cell receptor levels and B cell activation.

J. Immunol. 185(1) , 294-301, (2010)

Mechanisms by which cell surface levels of the BCR are regulated remain largely unknown. We found that B cells lacking the lysosomal-associated protein transmembrane 5 (LAPTM5) expressed higher levels...

The pericyte and stromal cell marker CD248 (endosialin) is required for efficient lymph node expansion.

Eur. J. Immunol. 40(7) , 1884-9, (2010)

CD248 is a cell surface receptor that specifically identifies fibroblasts and pericytes during development and in association with cancer and inflammation. However, its function is poorly defined and ...

 Synonyms

EINECS 233-948-0
4-Hydroxy-3-nitrophenylacetic Acid
2-(4-Hydroxy-3-nitrophenyl)acetic acid
MFCD00007122
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