![]() Glycolic acid structure
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Common Name | Glycolic acid | ||
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CAS Number | 79-14-1 | Molecular Weight | 76.051 | |
Density | 1.4±0.1 g/cm3 | Boiling Point | 265.6±13.0 °C at 760 mmHg | |
Molecular Formula | C2H4O3 | Melting Point | 75-80 °C(lit.) | |
MSDS | Chinese USA | Flash Point | 128.7±16.3 °C | |
Symbol |
![]() ![]() GHS05, GHS07 |
Signal Word | Danger |
Use of Glycolic acidGlycolic Acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour. |
Name | glycolic acid |
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Synonym | More Synonyms |
Description | Glycolic Acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour. |
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Related Catalog | |
Target |
Human Endogenous Metabolite |
In Vitro | Different concentrations of Glycolic Acid (GA) or LA (300 and 500 mg/mL) are tested on the growth of mouse and human melanoma cells. Both types of cells grow well, even in the presence of 300 mg/mL of each chemical for 5 days. However, 500 mg/mL Glycolic Acid inhibits the cell growth of mouse melanoma cells (41%) and humanmelanoma cells (27%), and 500 mg/mL of LA inhibits the growth of mouse melanoma cells (36%)[1]. |
Cell Assay | HM3KO pigmented human melanoma cells and B16 mouse melanoma cells are cultured in Dulbecco’s modified Eagles medium supplemented with 10%fetal calf serum and appropriate amounts of antibiotics and fungizone were dissolved at a concentration of 100mg/mL in distilled water. These chemicals (e.g., Glycolic Acid ) are added to the cell cultures at final concentrations of 300 or 500 mg/mL every 2 days for 5 days[1]. |
References |
Density | 1.4±0.1 g/cm3 |
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Boiling Point | 265.6±13.0 °C at 760 mmHg |
Melting Point | 75-80 °C(lit.) |
Molecular Formula | C2H4O3 |
Molecular Weight | 76.051 |
Flash Point | 128.7±16.3 °C |
Exact Mass | 76.016045 |
PSA | 57.53000 |
LogP | -1.05 |
Vapour Pressure | 0.0±1.2 mmHg at 25°C |
Index of Refraction | 1.450 |
Storage condition | 2-8°C |
Stability | Stable. Incompatible with bases, oxidizing agents and reducing agents. |
Water Solubility | SOLUBLE |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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Symbol |
![]() ![]() GHS05, GHS07 |
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Signal Word | Danger |
Hazard Statements | H314-H332 |
Precautionary Statements | P261-P280-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338 |
Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
Hazard Codes | C:Corrosive |
Risk Phrases | R22;R34 |
Safety Phrases | S26-S36/37/39-S45-S23 |
RIDADR | UN 3265 8/PG 3 |
WGK Germany | 1 |
RTECS | MC5250000 |
Packaging Group | II |
Hazard Class | 8 |
HS Code | 2918199090 |
Precursor 9 | |
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DownStream 10 | |
HS Code | 2918199090 |
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Summary | 2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
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Physiology and pathophysiology of organic acids in cerebrospinal fluid.
J. Inherit. Metab. Dis. 16(4) , 648-69, (1993) Concentrations of organic acids in cerebrospinal fluid (CSF) appear to be directly dependent upon their rate of production in the brain. There is evidence that the net release of short-chain monocarbo... |
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HMDB: a knowledgebase for the human metabolome.
Nucleic Acids Res. 37(Database issue) , D603-10, (2009) The Human Metabolome Database (HMDB, http://www.hmdb.ca) is a richly annotated resource that is designed to address the broad needs of biochemists, clinical chemists, physicians, medical geneticists, ... |
Glycocide |
QV1Q |
CHC-22 |
2-Hydroxyethanoic acid |
Acetic acid, 2-hydroxy- |
GlyPure 99 |
hydroxyacetic acid |
HOCH2COOH |
Glykolsure |
Glycol acid |
GlyPure 70 |
EINECS 201-180-5 |
a-Hydroxyacetic acid |
Glycollic acid |
Glycolic acid |
methoxycarboxylic acid |
GLYCOLATE |
GlyPure |
MFCD00004312 |
glycolic |