Lei-Dab 7 TFA

Modify Date: 2024-01-10 17:17:12

Lei-Dab 7 TFA Structure
Lei-Dab 7 TFA structure
Common Name Lei-Dab 7 TFA
CAS Number 1061556-49-7 Molecular Weight 3394.07
Density N/A Boiling Point N/A
Molecular Formula C141H236N46O39S6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Lei-Dab 7 TFA


Lei-Dab7 is a high affinity, selective KCa2.2 (SK2) channel blocker (Kd=3.8 nM). Lei-Dab7 exhibits >200-fold selectivity for KCa2.2 over KCa2.1, KCa2.3, KCa3.1, Kv and Kir2.1. Lei-Dab7 increases theta-burst responses and increases LTP in rat hippocampal slices in vitro.

 Names

Name (Dab7)-Leiurotoxin I

 Lei-Dab 7 TFA Biological Activity

Description Lei-Dab7 is a high affinity, selective KCa2.2 (SK2) channel blocker (Kd=3.8 nM). Lei-Dab7 exhibits >200-fold selectivity for KCa2.2 over KCa2.1, KCa2.3, KCa3.1, Kv and Kir2.1. Lei-Dab7 increases theta-burst responses and increases LTP in rat hippocampal slices in vitro.
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 Chemical & Physical Properties

Molecular Formula C141H236N46O39S6
Molecular Weight 3394.07
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