acetic acid-[2-(5-chloro-2-nitro-phenylsulfanyl)-anilide]

Modify Date: 2024-01-05 21:22:00

acetic acid-[2-(5-chloro-2-nitro-phenylsulfanyl)-anilide] Structure
acetic acid-[2-(5-chloro-2-nitro-phenylsulfanyl)-anilide] structure
Common Name acetic acid-[2-(5-chloro-2-nitro-phenylsulfanyl)-anilide]
CAS Number 107522-19-0 Molecular Weight 322.76700
Density N/A Boiling Point N/A
Molecular Formula C14H11ClN2O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of acetic acid-[2-(5-chloro-2-nitro-phenylsulfanyl)-anilide]


PDE7-IN-2 (compound 2) is a potent PDE7 (phosphodiesterase 7) inhibitor with IC50 value of 2.1 µM. PDE7-IN-2 has the potential for the research of parkinson’s disease[1].

 Names

Name acetic acid-[2-(5-chloro-2-nitro-phenylsulfanyl)-anilide]
Synonym More Synonyms

  Biological Activity

Description PDE7-IN-2 (compound 2) is a potent PDE7 (phosphodiesterase 7) inhibitor with IC50 value of 2.1 µM. PDE7-IN-2 has the potential for the research of parkinson’s disease[1].
Related Catalog
Target

PDE7A:2.1 μM (IC50)

References

[1]. García AM, wt, al. Modulation of cAMP-specific PDE without emetogenic activity: new sulfide-like PDE7 inhibitors. J Med Chem. 2014 Oct 23;57(20):8590-607.

 Chemical & Physical Properties

Molecular Formula C14H11ClN2O3S
Molecular Weight 322.76700
Exact Mass 322.01800
PSA 100.22000
LogP 4.95400

 Precursor & DownStream

Precursor  0

DownStream  1

 Synonyms

Essigsaeure-[2-(5-chlor-2-nitro-phenylmercapto)-anilid]
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