Secretin (human)

Modify Date: 2024-01-02 16:51:28

Secretin (human) structure	Common Name	Secretin (human)
	CAS Number	108153-74-8	Molecular Weight	3039.409
	Density	1.5±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₃₀H₂₂₀N₄₄O₄₀	Melting Point	N/A
	MSDS	Chinese USA	Flash Point	N/A

Use of Secretin (human)

Secretin (28-54), human is a 27-amino acid residue C-terminally amidated peptide, which acts on secretin receptors.

Name	Secretin
Synonym	More Synonyms

Description	Secretin (28-54), human is a 27-amino acid residue C-terminally amidated peptide, which acts on secretin receptors.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Neurological Disease Peptides Research Areas >> Metabolic Disease
Target	Human secretin receptor[1]
In Vitro	Secretin (28-54), human (Human secretin) binds to secretin receptors on the presynaptic membrane or on the Purkinje cell membrane[1]. Secretin (28-54), human (Human secretin) enhances the secretion of bicarbonate, enzymes, and K+ from the pancreas.Secretin (28-54), human is expressed in the hypothalamus and pituitary gland, and Secretin (28-54), human inhibits adrenocorticotropic hormone (ACTH) release.Secretin (28-54), human selectively depresses the glucocorticoid response to ACTH of dispersed zona fasciculata-reticularis (ZF/R) cells[2]. Secretin (28-54), human (Human secretin) is a 27-amino acid peptide and is the active form of pro-secretin, which is known as a preprohormone and is synthesized as a larger precursor like other regulatory peptides. Secretin is secreted by S cells in the small intestine and affects the function of a number of organ systems. Secretin receptors (SR) are expressed in the basolateral domain of several cell types. Secretin is a member of the secretin-glucagon family and is secreted by S cells of the duodenum in the crypts of Lieberkühn. Secretin affects the function of a number of organ systems and cell types. Secretin exerts its biological effects through G-protein coupled secretin receptors (SR), which are expressed in the basolateral domain of several cells. In addition to regulating the pH of the duodenal content by the control of gastric acid secretion, secretin regulates the secretion of bicarbonate ions into the duodenum from the epithelia lining the pancreatic and biliary ducts[3].
References	[1]. Ng SS, et al. Secretin as a neuropeptide. Mol Neurobiol. 2002 Aug;26(1):97-107. [2]. Nussdorfer GG, et al. Secretin, glucagon, gastric inhibitory polypeptide, parathyroid hormone, and related peptides in the regulation of the hypothalamus- pituitary-adrenal axis. Peptides. 2000 Feb;21(2):309-24. [3]. Afroze S, et al. The physiological roles of secretin and its receptor. Ann Transl Med. 2013 Oct;1(3):29.

Density	1.5±0.1 g/cm3
Molecular Formula	C₁₃₀H₂₂₀N₄₄O₄₀
Molecular Weight	3039.409
Exact Mass	3037.653320
PSA	1401.22000
LogP	-8.42
Index of Refraction	1.657
Storage condition	−20°C

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	VS4030000

MFCD00135670

L-Histidyl-L-seryl-L-α-aspartylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-glutamyl-L-leucyl-L-seryl-L-arginyl-L-leucyl-L-arginyl-L-α-glutamylglycyl-L-alanyl-L-arginyl-L-leucyl -L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminylglycyl-L-leucyl-L-valinamide

L-Histidyl-L-seryl-L-α-aspartylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-glutamyl-L-leucyl-L-seryl-L-arginyl-L-leucyl-L-arginyl-L-α-glutamylglycyl-L-alanyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminylglycyl-L-leucyl-L-valinamide

L-Valinamide, L-histidyl-L-seryl-L-α-aspartylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-glutamyl-L-leucyl-L-seryl-L-arginyl-L-leucyl-L-arginyl-L-α-glutamylglycyl-L-alanyl-L-arginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminylglycyl-L-leucyl-

L-Valinamide, L-histidyl-L-seryl-L-α-aspartylglycyl-L-threonyl-L-phenylalanyl-L-threonyl-L-seryl-L-α-glutamyl-L-leucyl-L-seryl-L-arginyl-L-leucyl-L-arginyl-L-α-glutamylglycyl-L-alanyl-L-ar ginyl-L-leucyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-glutaminylglycyl-L-leucyl-

secretin human

HIS-SER-ASP-GLY-THR-PHE-THR-SER-GLU-LEU-SER-ARG-LEU-ARG-GLU-GLY-ALA-ARG-LEU-GLN-ARG-LEU-LEU-GLN-GLY-LEU-VAL-NH2

HSDGTFTSELSRLREGARLQRLLQGLV-NH3

Secretin (28-54), human

GL Biochem (Shanghai) Ltd.
China
Product Name: HSDGTFTSELSRLREGARLQRLLQGLV-NH3
Price: $Inquiry/1g
Purity: 98.0%
Stocking Period: Inquiry
Contact: Jackie Yang

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Secretin (human)
Price: ￥2368.0/2mg ￥4168.0/5mg ￥1398.0/1mg
Purity: 97.0%
Stocking Period: Inquiry
Contact: Liu jia

Nanjing Peptide Biotech Ltd
China
Product Name: Secretin
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Stocking Period: 7 Day
Contact: jom

Zhejiang Hangyu API Co., Ltd
China
Product Name: Secretin (human)
Price: $Inquiry/1kg
Purity: 99.0%
Stocking Period: 1 Day
Contact: Vinnie

Get all suppliers and price by the below link:

Secretin (human) suppliers

Price: $120/1mg

Reference only. check more Secretin (human) price

Secretin (human)

Use of Secretin (human)

Names

Secretin (human) Biological Activity

Chemical & Physical Properties

Safety Information

Synonyms