NSC130813
Modify Date: 2024-01-05 22:10:12
NSC130813 structure
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Common Name | NSC130813 | ||
|---|---|---|---|---|
| CAS Number | 1082532-95-3 | Molecular Weight | 572.354 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C26H30Cl4N4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NSC130813HM03 trihydrochloride is a potent and selective HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) inhibitor. HM03 trihydrochloride has anticancer activity[1]. |
| Name | NERI02 |
|---|---|
| Synonym | More Synonyms |
| Description | HM03 trihydrochloride is a potent and selective HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) inhibitor. HM03 trihydrochloride has anticancer activity[1]. |
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| Related Catalog | |
| In Vitro | HM03 trihydrochloride (0.1-50 μM; 72 hours) exhibits over 50% inhibition at 25 µM concentration in HCT116 cells[1]. HM03 trihydrochloride forms more binding interactions with HSPA5 and HSPA9 than with the other HSP70 proteins[1]. HM03 trihydrochloride exhibits promising inhibition activities from cancer cell viability and tumor inhibition assays[1]. |
| References |
| Molecular Formula | C26H30Cl4N4O2 |
|---|---|
| Molecular Weight | 572.354 |
| Exact Mass | 570.112305 |
| Storage condition | ?20°C |
| RIDADR | NONH for all modes of transport |
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| 4-[(6-Chloro-2-methoxy-9-acridinyl)amino]-2-[(4-methyl-1-piperazinyl)methyl]phenol trihydrochloride |
| Phenol, 4-[(6-chloro-2-methoxy-9-acridinyl)amino]-2-[(4-methyl-1-piperazinyl)methyl]-, hydrochloride (1:3) |
| MFCD27978378 |