TC-S 7005

Modify Date: 2024-01-12 18:39:09

TC-S 7005 Structure
TC-S 7005 structure
Common Name TC-S 7005
CAS Number 1082739-92-1 Molecular Weight 359.38
Density N/A Boiling Point N/A
Molecular Formula C21H17N3O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TC-S 7005


TC-S 7005 is a Polo-like kinases (Plks) inhibitor with IC50s of 4 nM, 24 nM and 214 nM for Plk2, Plk3, and Plk1, respectively[1].

 Names

Name TC-S 7005

 TC-S 7005 Biological Activity

Description TC-S 7005 is a Polo-like kinases (Plks) inhibitor with IC50s of 4 nM, 24 nM and 214 nM for Plk2, Plk3, and Plk1, respectively[1].
Related Catalog
Target

PLK2:4 nM (IC50)

PLK3:24 nM (IC50)

PLK1:214 nM (IC50)

References

[1]. Hanan EJ, et al. Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors. Bioorg Med Chem Lett. 2008 Oct 1;18(19):5186-9.

 Chemical & Physical Properties

Molecular Formula C21H17N3O3
Molecular Weight 359.38
Storage condition -20°C