TC-I 2000

Modify Date: 2025-09-12 23:12:57

TC-I 2000 Structure
TC-I 2000 structure
Common Name TC-I 2000
CAS Number 1159996-20-9 Molecular Weight 414.39500
Density N/A Boiling Point N/A
Molecular Formula C23H18F4N2O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TC-I 2000


TRPM8-IN-1 (example 14) is an inhibitor of transient receptor potential melastatin-8 (TRPM8) channels, IC50<5 μM[1].

 Names

Name N-(4-fluorophenyl)-1-(4-(trifluoromethyl)phenyl)-3,4-dihydroisoquinoline-2(1H)-carboxamide
Synonym More Synonyms

 TC-I 2000 Biological Activity

Description TRPM8-IN-1 (example 14) is an inhibitor of transient receptor potential melastatin-8 (TRPM8) channels, IC50<5 μM[1].
Related Catalog
Target

TRPM8:<5 μM (IC50)

References

[1]. Norman, et al. Preparation of substituted dihydroisoquinoline derivatives for use as TRP-M8 receptor ligands. World Intellectual Property Organization, WO2009073203 A1. 2009-06-11.

 Chemical & Physical Properties

Molecular Formula C23H18F4N2O
Molecular Weight 414.39500
Exact Mass 414.13600
PSA 32.34000
LogP 6.03500

 Synonyms

sb 611812
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