S961

Modify Date: 2024-01-03 01:19:23

S961 Structure
S961 structure
Common Name S961
CAS Number 1083433-49-1 Molecular Weight 4804.13
Density N/A Boiling Point N/A
Molecular Formula C211H297N55O71S2 Melting Point N/A
MSDS USA Flash Point N/A

 Use of S961


S961 is an high-affinity and selective insulin receptor (IR) antagonist with IC50s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively[1].

 Names

Name S961

 S961 Biological Activity

Description S961 is an high-affinity and selective insulin receptor (IR) antagonist with IC50s of 0.048, 0.027, and 630 nM for HIR-A, HIR-B, and human insulin-like growth factor I receptor (HIGF-IR) in SPA-assay, respectively[1].
Related Catalog
In Vitro S961 also shows high-affinity to Rat IR and Pig IR with IC50s of 0.056 nM and 0.084 nM in PEG-assay, respectively[1].
References

[1]. Schäffer L, et al. A novel high-affinity peptide antagonist to the insulin receptor. Biochem Biophys Res Commun. 2008 Nov 14;376(2):380-3.

 Chemical & Physical Properties

Molecular Formula C211H297N55O71S2
Molecular Weight 4804.13
Storage condition -20°C

 Safety Information

RIDADR NONH for all modes of transport