LUMICHROME
LUMICHROME structure
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Common Name | LUMICHROME | ||
|---|---|---|---|---|
| CAS Number | 1086-80-2 | Molecular Weight | 242.23300 | |
| Density | 1.388g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C12H10N4O2 | Melting Point | 300 °C | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of LUMICHROMELumichrome, a photodegradation product of Riboflavin, is an endogenous compound in humans. Lumichrome inhibits human lung cancer cell growth and induces apoptosis via a p53-dependent mechanism[1][2]. |
| Name | lumichrome |
|---|---|
| Synonym | More Synonyms |
| Description | Lumichrome, a photodegradation product of Riboflavin, is an endogenous compound in humans. Lumichrome inhibits human lung cancer cell growth and induces apoptosis via a p53-dependent mechanism[1][2]. |
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| Related Catalog | |
| Target |
Human Endogenous Metabolite |
| References |
| Density | 1.388g/cm3 |
|---|---|
| Melting Point | 300 °C |
| Molecular Formula | C12H10N4O2 |
| Molecular Weight | 242.23300 |
| Exact Mass | 242.08000 |
| PSA | 91.50000 |
| LogP | 0.77640 |
| Index of Refraction | 1.66 |
| InChIKey | ZJTJUVIJVLLGSP-UHFFFAOYSA-N |
| SMILES | Cc1cc2nc3[nH]c(=O)[nH]c(=O)c3nc2cc1C |
| Stability | Stable. Incompatible with strong oxidizing agents. Combustible. |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| Safety Phrases | S24/25 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2933990090 |
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Enhanced Indirect Photochemical Transformation of Histidine and Histamine through Association with Chromophoric Dissolved Organic Matter.
Environ. Sci. Technol. 49 , 5511-9, (2015) Photochemical transformations greatly affect the stability and fate of amino acids (AAs) in sunlit aquatic ecosystems. Whereas the direct phototransformation of dissolved AAs is well investigated, the... |
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The B vitamins nicotinamide (B3) and riboflavin (B2) stimulate metamorphosis in larvae of the deposit-feeding polychaete Capitella teleta: implications for a sensory ligand-gated ion channel.
PLoS ONE 9(11) , e109535, (2014) Marine sediments can contain B vitamins, presumably incorporated from settled, decaying phytoplankton and microorganisms associated with decomposition. Because B vitamins may be advantageous for the e... |
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Molecular and functional characterization of riboflavin specific transport system in rat brain capillary endothelial cells.
Brain Res. 1468 , 1-10, (2012) Riboflavin is an important water soluble vitamin (B2) required for metabolic reactions, normal cellular growth, differentiation and function. Mammalian brain cells cannot synthesize riboflavin and mus... |
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Name: USP8 deubiquitinase inhibition: Primary qHTS
Source: 24642
Target: ubiquitin specific peptidase 8
External Id: USP8 FAST DUB HTS Primary
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Name: Experimentally measured binding affinity data (Kd) for protein-ligand complexes deriv...
Source: Shanghai Institute of Organic Chemistry
Target: N/A
External Id: PDBbind-Kd for protein-ligand complexes
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Name: USP17 deubiquitinase inhibition: Primary qHTS
Source: 24642
Target: ubiquitin specific peptidase 17 like family member 5
External Id: USP17 FAST DUB HTS Primary
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Name: USP7 deubiquitinase inhibition: Primary qHTS
Source: 24642
Target: ubiquitin specific peptidase 7
External Id: USP7 FAST DUB HTS Primary
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Name: Rescue cell viability in cybrid cells with a genetic mutation in complex 1 of the mit...
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: N/A
External Id: HMS1315
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Name: Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ...
Source: ChEMBL
Target: Klebsiella pneumoniae
External Id: CHEMBL4296186
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Name: Assays to identify small molecules inhibitory for eIF4E expression
Source: 13133
Target: N/A
External Id: 20160513eIF4E
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Name: Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress
Source: ICCB-Longwood/NSRB Screening Facility, Harvard Medical School
Target: HCMV UL50
External Id: HMS1262
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Name: Inhibition of Mycobacterium tuberculosis Uracil-DNA glycosylase using 5' 32P end-labe...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5623086
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Name: Inhibition of Mycobacterium tuberculosis Uracil-DNA glycosylase using 5'-FAM-CUUUUUGA...
Source: ChEMBL
Target: N/A
External Id: CHEMBL5623087
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| MFCD00005021 |
| 7,8-Dimethylalloxazine |
| LUM |
| flavins |
| 7,8-dimethyl-1H-benzo[g]pteridine-2,4-dione |
| 6,7-DIMETHYLALLOXAZINE |
| EINECS 214-120-8 |
| Benzo[g]pteridine-2,4(1H,3H)-dione,7,8-dimethyl |
| 7,8-dimethyl-benzo[g]pteridine-2,4(1H,3H)-dione |