LUMICHROME

Modify Date: 2024-01-02 17:40:31

LUMICHROME Structure
LUMICHROME structure
Common Name LUMICHROME
CAS Number 1086-80-2 Molecular Weight 242.23300
Density 1.388g/cm3 Boiling Point N/A
Molecular Formula C12H10N4O2 Melting Point 300 °C
MSDS Chinese USA Flash Point N/A

 Use of LUMICHROME


Lumichrome, a photodegradation product of Riboflavin, is an endogenous compound in humans. Lumichrome inhibits human lung cancer cell growth and induces apoptosis via a p53-dependent mechanism[1][2].

 Names

Name lumichrome
Synonym More Synonyms

 LUMICHROME Biological Activity

Description Lumichrome, a photodegradation product of Riboflavin, is an endogenous compound in humans. Lumichrome inhibits human lung cancer cell growth and induces apoptosis via a p53-dependent mechanism[1][2].
Related Catalog
Target

Human Endogenous Metabolite

References

[1]. Bergh VJ, et al. Influence of formulation on photoinactivation of bacteria by lumichrome. Pharmazie. 2015;70(9):574-580.

[2]. Chantarawong W, et al. Lumichrome Inhibits Human Lung Cancer Cell Growth and Induces Apoptosis via a p53-Dependent Mechanism. Nutr Cancer. 2019;71(8):1390-1402.

 Chemical & Physical Properties

Density 1.388g/cm3
Melting Point 300 °C
Molecular Formula C12H10N4O2
Molecular Weight 242.23300
Exact Mass 242.08000
PSA 91.50000
LogP 0.77640
Index of Refraction 1.66
Stability Stable. Incompatible with strong oxidizing agents. Combustible.

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases S24/25
RIDADR NONH for all modes of transport
HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles32

More Articles
Enhanced Indirect Photochemical Transformation of Histidine and Histamine through Association with Chromophoric Dissolved Organic Matter.

Environ. Sci. Technol. 49 , 5511-9, (2015)

Photochemical transformations greatly affect the stability and fate of amino acids (AAs) in sunlit aquatic ecosystems. Whereas the direct phototransformation of dissolved AAs is well investigated, the...

The B vitamins nicotinamide (B3) and riboflavin (B2) stimulate metamorphosis in larvae of the deposit-feeding polychaete Capitella teleta: implications for a sensory ligand-gated ion channel.

PLoS ONE 9(11) , e109535, (2014)

Marine sediments can contain B vitamins, presumably incorporated from settled, decaying phytoplankton and microorganisms associated with decomposition. Because B vitamins may be advantageous for the e...

Molecular and functional characterization of riboflavin specific transport system in rat brain capillary endothelial cells.

Brain Res. 1468 , 1-10, (2012)

Riboflavin is an important water soluble vitamin (B2) required for metabolic reactions, normal cellular growth, differentiation and function. Mammalian brain cells cannot synthesize riboflavin and mus...

 Synonyms

MFCD00005021
7,8-Dimethylalloxazine
LUM
flavins
7,8-dimethyl-1H-benzo[g]pteridine-2,4-dione
6,7-DIMETHYLALLOXAZINE
EINECS 214-120-8
Benzo[g]pteridine-2,4(1H,3H)-dione,7,8-dimethyl
7,8-dimethyl-benzo[g]pteridine-2,4(1H,3H)-dione
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