H-Arg-Gly-Asp-Cys-OH trifluoroacetate salt

Modify Date: 2024-01-04 17:26:13

H-Arg-Gly-Asp-Cys-OH trifluoroacetate salt structure	Common Name	H-Arg-Gly-Asp-Cys-OH trifluoroacetate salt
	CAS Number	109292-46-8	Molecular Weight	449.48300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₅H₂₇N₇O₇S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of H-Arg-Gly-Asp-Cys-OH trifluoroacetate salt

Arg-Gly-Asp-Cys is the binding motif of fibronectin to cell adhesion molecules, and can inhibit platelet aggregation and fibrinogen binding.

Name	h-arg-gly-asp-cys-oh
Synonym	More Synonyms

Description	Arg-Gly-Asp-Cys is the binding motif of fibronectin to cell adhesion molecules, and can inhibit platelet aggregation and fibrinogen binding.
Related Catalog	Signaling Pathways >> Others >> Others Peptides Research Areas >> Others
In Vitro	RGDC immobilizes peptide onto DAH-CMTMC is found to be about 15.3 μg/mg of chitosan derivative by amino acid analysis (AAA). RGDC-functionalized chitosan may lead to enhanced wound healing (viability >140%). RGDC-functionalizes chitosan derivatives exhibit in vitro wound healing properties by enhancing fibroblast proliferation and adhesion. RGDC-DAH-CMTMC favors cell growth and an increase in cellular proliferation compared to the control cells[1].
Cell Assay	Human precursor dermal fibroblasts (HDF, human dermal progenitor cells, 12 week male donor) are use in the assay. WST-1 assay is used to assess the viability of HDF when incubated with chitosan derivatives. For this study, HDF are seeded in a 96-well plate at a density of 6×103 cells/cm2. To each well, 100 μL of cell suspension is added and incubated for 48 h in order to allow cell attachment. DMEM is then replaced by 100 μL of CMTMC and RGDC-DAH-CMTMC suspension at concentrations of 0.25 mg/mL, 0.5 mg/mL and 1 mg/mL, respectively. Cell viability under polymer incubation is evaluated during 2, 4 and 7 days. SDS (1%) is used as negative control. The polymer solution is changed every 3 days. 100 μL of WST-1 (1:10 dilution in DMEM) are added in each well after removing the polymer suspension and incubated for 0.5-2 h. Absorbance is recorded with a BioTek Microplate reader at two different wavelengths (450 and 690 nm). The viability is presented as percentage compared to the positive control group (cells in DMEM supplemented with 10% fetal calf serum). All experiments are carried out in triplicates.
References	[1]. Patrulea V, et al. Peptide-decorated chitosan derivatives enhance fibroblast adhesion and proliferation in wound healing. Carbohydr Polym. 2016 May 20;142:114-23.

Molecular Formula	C₁₅H₂₇N₇O₇S
Molecular Weight	449.48300
Exact Mass	449.16900
PSA	288.62000
Storage condition	2-8℃

ARG-GLY-ASP-CYS

REF DUPL: H-Arg-Gly-Asp-Cys-OH

RGDC

R-G-D-C

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Arg-Gly-Asp-Cys
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

GL Biochem (Shanghai) Ltd.
China
Product Name: R-G-D-C
Price: $Inquiry/1g
Purity: 98.0%
Delivery: Inquiry
Contact: Jackie Yang
Email: ymbetter@glbiochem.com

Nanjing Peptide Biotech Ltd
China
Product Name: RGDC
Price: ￥Inquiry/10g ￥Inquiry/100g ￥Inquiry/1kg ￥Inquiry/10kg
Purity: 98.0%
Delivery: 7 Day
Contact: jom
Email: chenglong.fan@njpeptide.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: H-ARG-GLY-ASP-CYS-OH
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Price: $84/5mg

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