H-Arg-Gly-Asp-OH

Modify Date: 2024-01-09 13:25:52

H-Arg-Gly-Asp-OH Structure
H-Arg-Gly-Asp-OH structure
 Common Name H-Arg-Gly-Asp-OH
CAS Number 99896-85-2 Molecular Weight 346.340
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C12H22N6O6 Melting Point 153-155℃ (ethyl ether )
MSDS Chinese USA Flash Point N/A

 Use of H-Arg-Gly-Asp-OH


RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.

 Names

Name arg-gly-asp
Synonym More Synonyms

 H-Arg-Gly-Asp-OH Biological Activity

Description RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.
Related Catalog
Target

Integrin[1]

In Vitro RGD Trifluoroacetate is the most effective and most often employed peptide sequence for stimulated cell adhesion on synthetic surfaces. There are 24 integrins binding to ECM molecules in a RGD dependent manner: α3β1, α5β1, α8β1, αIIbβ3, αvβ1, αvβ3, αvβ5, αvβ6, αvβ8, and to some extent α2β1 and α4β1[1].
References

[1]. Hersel U, et al. RGD modified polymers: biomaterials for stimulated cell adhesion and beyond. Biomaterials. 2003 Nov;24(24):4385-415.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Melting Point 153-155℃ (ethyl ether )
Molecular Formula C12H22N6O6
Molecular Weight 346.340
Exact Mass 346.160095
PSA 220.72000
LogP -1.94
Index of Refraction 1.648
Storage condition −20°C
Water Solubility Soluble in 0.1N acetic acid at 20mg/ml

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2925290090

 Synthetic Route

H-Gly-Asp-OH structure

H-Gly-Asp-OH

CAS#:4685-12-5

Nα,NG,NG'-tri-Boc-L-arginine N-hydroxysuccinimide ester structure

Nα,NG,NG'-tri-B...

CAS#:108787-79-7

~52%

H-Arg-Gly-Asp-OH Structure

H-Arg-Gly-Asp-OH

CAS#:99896-85-2

Literature: Pharmaceutical Chemistry Journal, , vol. 32, # 12 p. 641 - 645
p-Cresol structure

p-Cresol

CAS#:106-44-5

Thiophenol structure

Thiophenol

CAS#:108-98-5

~%

H-Arg-Gly-Asp-OH Structure

H-Arg-Gly-Asp-OH

CAS#:99896-85-2

Literature: US2010/98748 A1, ;
Z-Gly-Asp(OBu)-OH structure

Z-Gly-Asp(OBu)-OH

CAS#:131668-52-5

~%

H-Arg-Gly-Asp-OH Structure

H-Arg-Gly-Asp-OH

CAS#:99896-85-2

Literature: Pharmaceutical Chemistry Journal, , vol. 32, # 12 p. 641 - 645

 Customs

HS Code 2925290090
Summary 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles63

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 Synonyms

L-Aspartic acid, L-arginylglycyl-
F-336
L-Arginylglycyl-L-aspartic acid
L-Aspartic acid, N-(diaminomethylene)-L-ornithylglycyl-
aspartic acid, N-[2-[[(1Z,2S)-2-amino-5-[(aminoiminomethyl)amino]-1-hydroxypentylidene]amino]-1-hydroxyethylidene]-, (Z)-
Arg-Gly-Asp (RGD)
arginyl-glycyl-aspartic acid
l-arginylglycylaspartic acid
RGD
Arg-Gly-Asp acetate
H2N-RGD-OH
N-(Diaminomethylene)-L-ornithylglycyl-L-aspartic acid
MFCD00057952
(2S)-2-({N-[(2S)-5-{[amino(iminio)methyl]amino}-2-ammoniopentanoyl]glycyl}amino)butanedioate
H-ARG-GLY-ASP-OH
Rgd tripeptide sequence
RGD (Arg-Gly-Asp) Peptides
RGD PEPTIDE (CORE)
N-(diaminomethylidene)-L-ornithylglycyl-L-aspartic acid
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