H-Arg-Gly-Asp-OH

Modify Date: 2024-01-09 13:25:52

H-Arg-Gly-Asp-OH Structure
H-Arg-Gly-Asp-OH structure
 Common Name H-Arg-Gly-Asp-OH
CAS Number 99896-85-2 Molecular Weight 346.340
Density 1.6±0.1 g/cm3 Boiling Point N/A
Molecular Formula C12H22N6O6 Melting Point 153-155℃ (ethyl ether )
MSDS Chinese USA Flash Point N/A

 Use of H-Arg-Gly-Asp-OH


RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.

 Names

Name arg-gly-asp
Synonym More Synonyms

 H-Arg-Gly-Asp-OH Biological Activity

Description RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and elicits specific cell responses; binds to integrins.
Related Catalog
Target

Integrin[1]
In Vitro RGD Trifluoroacetate is the most effective and most often employed peptide sequence for stimulated cell adhesion on synthetic surfaces. There are 24 integrins binding to ECM molecules in a RGD dependent manner: α3β1, α5β1, α8β1, αIIbβ3, αvβ1, αvβ3, αvβ5, αvβ6, αvβ8, and to some extent α2β1 and α4β1[1].
References

[1]. Hersel U, et al. RGD modified polymers: biomaterials for stimulated cell adhesion and beyond. Biomaterials. 2003 Nov;24(24):4385-415.

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Melting Point 153-155℃ (ethyl ether )
Molecular Formula C12H22N6O6
Molecular Weight 346.340
Exact Mass 346.160095
PSA 220.72000
LogP -1.94
Index of Refraction 1.648
Storage condition −20°C
Water Solubility Soluble in 0.1N acetic acid at 20mg/ml

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes Xi
RIDADR NONH for all modes of transport
WGK Germany 3
HS Code 2925290090

 Synthetic Route

H-Gly-Asp-OH structure

H-Gly-Asp-OH

CAS#:4685-12-5
Nα,NG,NG'-tri-Boc-L-arginine N-hydroxysuccinimide ester structure

Nα,NG,NG'-tri-B...

CAS#:108787-79-7

~52%

H-Arg-Gly-Asp-OH Structure

H-Arg-Gly-Asp-OH

CAS#:99896-85-2
Literature: Pharmaceutical Chemistry Journal, , vol. 32, # 12 p. 641 - 645
p-Cresol structure

p-Cresol

CAS#:106-44-5
Thiophenol structure

Thiophenol

CAS#:108-98-5

~%

H-Arg-Gly-Asp-OH Structure

H-Arg-Gly-Asp-OH

CAS#:99896-85-2
Literature: US2010/98748 A1, ;
Z-Gly-Asp(OBu)-OH structure

Z-Gly-Asp(OBu)-OH

CAS#:131668-52-5

~%

H-Arg-Gly-Asp-OH Structure

H-Arg-Gly-Asp-OH

CAS#:99896-85-2
Literature: Pharmaceutical Chemistry Journal, , vol. 32, # 12 p. 641 - 645

 Customs

HS Code 2925290090
Summary 2925290090 other imines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

 Articles63

More Articles
Coculture of dorsal root ganglion neurons and differentiated human corneal stromal stem cells on silk-based scaffolds.

J. Biomed. Mater. Res. A 103 , 3339-48, (2015)

Corneal tissue displays the highest peripheral nerve density in the human body. Engineering of biomaterials to promote interactions between neurons and corneal tissue could provide tissue models for n...
Inducing cells to disperse nickel nanowires via integrin-mediated responses.

Nanotechnology 26(13) , 135102, (2015)

We present non-cytotoxic, magnetic, Arg-Gly-Asp (RGD)-functionalized nickel nanowires (RGD-nanowires) that trigger specific cellular responses via integrin transmembrane receptors, resulting in disper...
Improved tumor-targeting MRI contrast agents: Gd(DOTA) conjugates of a cycloalkane-based RGD peptide.

Biochem. Biophys. Res. Commun. 455(3-4) , 246-50, (2014)

Two new MRI contrast agents, Gd-DOTA-c(RGD-ACP-K) (1) and Gd-DOTA-c(RGD-ACH-K) (2), which were designed by incorporating aminocyclopentane (ACP)- or aminocyclohexane (ACH)-carboxylic acid into Gd-DOTA...

 Synonyms

L-Aspartic acid, L-arginylglycyl-
F-336
L-Arginylglycyl-L-aspartic acid
L-Aspartic acid, N-(diaminomethylene)-L-ornithylglycyl-
aspartic acid, N-[2-[[(1Z,2S)-2-amino-5-[(aminoiminomethyl)amino]-1-hydroxypentylidene]amino]-1-hydroxyethylidene]-, (Z)-
Arg-Gly-Asp (RGD)
arginyl-glycyl-aspartic acid
l-arginylglycylaspartic acid
RGD
Arg-Gly-Asp acetate
H2N-RGD-OH
N-(Diaminomethylene)-L-ornithylglycyl-L-aspartic acid
MFCD00057952
(2S)-2-({N-[(2S)-5-{[amino(iminio)methyl]amino}-2-ammoniopentanoyl]glycyl}amino)butanedioate
H-ARG-GLY-ASP-OH
Rgd tripeptide sequence
RGD (Arg-Gly-Asp) Peptides
RGD PEPTIDE (CORE)
N-(diaminomethylidene)-L-ornithylglycyl-L-aspartic acid
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  • Product Name: Arg-Gly-Asp
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  • Purity: 98.0%
  • Stocking Period: 3 Day
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