ERK2 IN-1

Modify Date: 2025-08-27 17:34:04

ERK2 IN-1 Structure
ERK2 IN-1 structure
 Common Name ERK2 IN-1
CAS Number 1093061-47-2 Molecular Weight 647.76
Density N/A Boiling Point N/A
Molecular Formula C36H34FN7O2S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ERK2 IN-1


ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM[1].

 Names

Name ERK2 IN-1

 ERK2 IN-1 Biological Activity

Description ERK2 IN-1 is a selective ERK2 inhibitor with an IC50 of 7 nM[1].
Related Catalog
Target

ERK2:7 nM (IC50)

In Vitro ERK1/2 IN-1 (Compound 28) maintains good ERK enzymatic activity (ERK IC50=7 nM) and cellular activity in BRAF/KRAS mutant wildtype cancer cell lines (HT-29/Caspase IC50=118/80 nM)[1].
References

[1]. Boga SB, Discovery of 3(S)-thiomethyl pyrrolidine ERK inhibitors for oncology. Bioorg Med Chem Lett. 2018 Jun 15;28(11):2029-2034.

 Chemical & Physical Properties

Molecular Formula C36H34FN7O2S
Molecular Weight 647.76
InChIKey UHRFQLODOGBNCC-BHVANESWSA-N
SMILES CSC1(C(=O)Nc2ccc3[nH]nc(-c4ccc(F)cc4)c3c2)CCN(CC(=O)N2CC=C(c3ccc(-c4ncccn4)cc3)CC2)C1
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here

Get all suppliers and price by the below link:

ERK2 IN-1 suppliers

ERK2 IN-1 price

Related Compounds: More...
LDH-IN-1
1964515-43-2
eIF4E-IN-1
2573979-31-2
HIV-IN-1
2756837-91-7
DUBs-IN-1
924296-18-4
HCVP-IN-1
877225-09-7
CLK1-IN-1
2123491-32-5
mTOR-IN-1
1207358-59-5
HAT-IN-1
1889281-94-0
USP7-IN-1
1381291-36-6
(R)-(2R,3R,3aR,4aS,5aR,5bR)-5a-(Bis(4-methoxyphenyl)(phenyl)methoxy)-3-fluoro-2-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)octahydrocyclopropa[4,5]cyclopenta[1,2-b]furan-3a-yl (2-cyanoethyl) diisopropylphosphoramidite
1687764-67-5
(2R,3S,3aR,4aS,5aR,5bR)-2-(6-Benzamido-9H-purin-9-yl)-3-fluorooctahydrocyclopropa[4,5]cyclopenta[1,2-b]furan-3a,5a-diyl diacetate
2102535-61-3
(2R)-2-[3-cyclopropyl-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-4-(methylsulfanyl)butanoic acid
2648930-52-1
7,7'''-Bis(3,5-diethenylphenyl)dotriacontahydro-3,3'(2H,7'H):7',3''(7''H):7'',3'''(2'''H)-quater-3,5,1,7-[1,2,3,4]butanetetraylnaphthalene
1262527-77-4
(1S)-3-amino-1-(2,4,6-trifluorophenyl)propan-1-ol
2227900-32-3
14-(2-(4-(((Benzyloxy)carbonyl)amino)-2-oxopyrimidin-1(2H)-yl)acetyl)-2,2-dimethyl-8-(2-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)acetyl)-4,10-dioxo-3-oxa-5,8,11,14-tetraazahexadecan-16-oic acid
2407920-90-3
(2R,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-6-[7-cyclohexyl-2-(5-cyclohexylpentyl)-2-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxymethyl]heptoxy]-4,5-dihydroxy-2-(hydroxymethyl)oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
1423310-08-0
1-(3-Cyclohexyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrol-1-yl)-2,2-dimethylpropan-1-one
2624040-98-6
1-(3-Bromoprop-1-en-2-yl)-3,5-dimethoxybenzene
2228577-14-6
(4S)-4-[(2S)-butan-2-yl]-2-[(4S)-4-[(2S)-butan-2-yl]-1-(3-tert-butylphenyl)-4,5-dihydroimidazol-2-yl]-1-(3-tert-butylphenyl)-4,5-dihydroimidazole
2652038-38-3
Chemsrc provides ERK2 IN-1(CAS#:1093061-47-2) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of ERK2 IN-1 are included as well.>> amp version: ERK2 IN-1

Home | MSDS/SDS Database Search | Journals | Product Classification | Biologically Active Compounds | Selling Leads | About Us | Disclaimer

Copyright © 2024 ChemSrc All Rights Reserved