TMEDA

Modify Date: 2024-01-02 07:48:09

TMEDA Structure
TMEDA structure
Common Name TMEDA
CAS Number 110-18-9 Molecular Weight 116.205
Density 0.8±0.1 g/cm3 Boiling Point 121.0±0.0 °C at 760 mmHg
Molecular Formula C6H16N2 Melting Point −55 °C(lit.)
MSDS Chinese USA Flash Point 10.0±0.0 °C
Symbol GHS02 GHS05 GHS07
GHS02, GHS05, GHS07
Signal Word Danger

 Names

Name N,N,N',N'-tetramethylethylenediamine
Synonym More Synonyms

 Chemical & Physical Properties

Density 0.8±0.1 g/cm3
Boiling Point 121.0±0.0 °C at 760 mmHg
Melting Point −55 °C(lit.)
Molecular Formula C6H16N2
Molecular Weight 116.205
Flash Point 10.0±0.0 °C
Exact Mass 116.131348
PSA 6.48000
LogP 0.30
Vapour Pressure 14.9±0.2 mmHg at 25°C
Index of Refraction 1.438
Stability Stable. Highly flammable. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, copper, mercury.
Water Solubility miscible

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KV7175000
CHEMICAL NAME :
Ethylenediamine, N,N,N',N'-tetramethyl-
CAS REGISTRY NUMBER :
110-18-9
LAST UPDATED :
199710
DATA ITEMS CITED :
13
MOLECULAR FORMULA :
C6-H16-N2
MOLECULAR WEIGHT :
116.24
WISWESSER LINE NOTATION :
1N1&2N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 30,63,1948
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
268 mg/kg
TOXIC EFFECTS :
Brain and Coverings - other degenerative changes Spinal Cord - other degenerative changes
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 15,19,1995
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1318 ppm/4H
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - ataxia Behavioral - irritability
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 8,249,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
630 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 28(6),55,1984
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
5390 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1230 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 15,19,1995
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Bird - quail
DOSE/DURATION :
>316 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 6,149,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 ppm/6H/11D-I
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - effect, not otherwise specified Endocrine - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0536165 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1174 No. of Facilities: 33 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 66 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1174 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 28 (estimated)

 Safety Information

Symbol GHS02 GHS05 GHS07
GHS02, GHS05, GHS07
Signal Word Danger
Hazard Statements H225-H302-H314-H332
Precautionary Statements P210-P280-P305 + P351 + P338-P310
Personal Protective Equipment Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes C:Corrosive
Risk Phrases R11;R20/22;R34
Safety Phrases S16-S26-S36/37/39-S45
RIDADR UN 2372 3/PG 2
WGK Germany 1
RTECS KV7175000
Packaging Group II
Hazard Class 3
HS Code 2921219000

 Synthetic Route

 Customs

HS Code 2921290000
Summary 2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

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 Synonyms

N,N,N′,N′ tetramethylethylenediamine
Tetrameen
N,N,N‘,N‘-Tetramethylethylenediamine,purified by redistillation,AcroSeal
EINECS 203-744-6
N,N,N',N'-Tetramethylethylenediamine
N,N,N`,N`-Tetramethylethylenediamine
1,2-Bis(dimethylamino)ethane,TEMED,TMEDA
Kaolizer 11
1,2-Bis(dimethylamino)ethane
N,N,N,N-Tetramethylethylenediamine
tetramethyldiaminoethane
N,N,N′,N′-tetramethyl-1,2-ethanediamine
N,N,N′,N′-tetramethylethylenediamine
Dabco TMEDA
n,n,n',n'-tetramethylethane-1,2-diamine
TEMED
1,2-Ethanediamine, N,N,N,N-tetramethyl-
Propamine D
N,N′-tetramethylethylenediamine
TMEDA
N,N,N',N'-tetramethyl-1,2-diaminoethane
Toyocat TE
N1,N1,N2,N2-Tetramethylethane-1,2-diamine
N,N,N',N'-Tetramethyl-1,2-ethanediamine
N,N,N′,N′-tetramethyl-1,2-diaminoethane
N,N,N‘,N‘-Tetramethylethylenediamine
ZnCl2*N,N,N,N-tetramethylethylenediamine
N,N,N‘,N‘-Tetramet
TMED
MFCD00008335
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