TMPDA

Modify Date: 2025-08-25 12:52:44

TMPDA structure	Common Name	TMPDA
	CAS Number	110-95-2	Molecular Weight	130.231
	Density	0.8±0.1 g/cm3	Boiling Point	143.3±8.0 °C at 760 mmHg
	Molecular Formula	C₇H₁₈N₂	Melting Point	N/A
	MSDS	USA	Flash Point	31.7±0.0 °C
	Symbol	GHS02, GHS05, GHS06	Signal Word	Danger

Name	N,N,N',N'-Tetramethyl-1,3-propanediamine
Synonym	More Synonyms

Density	0.8±0.1 g/cm3
Boiling Point	143.3±8.0 °C at 760 mmHg
Molecular Formula	C₇H₁₈N₂
Molecular Weight	130.231
Flash Point	31.7±0.0 °C
Exact Mass	130.147003
PSA	6.48000
LogP	0.43
Vapour Pressure	5.4±0.3 mmHg at 25°C
Index of Refraction	1.442
InChIKey	DMQSHEKGGUOYJS-UHFFFAOYSA-N
SMILES	CN(C)CCCN(C)C
Storage condition	Flammables area
Stability	Stable. Flammable. Incompatible with strong oxidizing agents, acids, acid chlorides, permanganates, carbon dioxide, nitrates, peroxides, nitrites, halogens.

TMPDA MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TX8400000

CHEMICAL NAME :: 1,3-Propanediamine, N,N,N',N'-tetramethyl-

CAS REGISTRY NUMBER :: 110-95-2

BEILSTEIN REFERENCE NO. :: 1734176

LAST UPDATED :: 199801

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C7-H18-N2

MOLECULAR WEIGHT :: 130.27

WISWESSER LINE NOTATION :: 1N1&3N1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 410 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 375 ppm/2H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: WADTAA Wright Air Development Center, Technical Report, U.S. Air Force. (Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: 55-250,10,1955

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 300 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - quail

DOSE/DURATION :: >316 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 6,149,1982 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 12 ppm/6H/30D-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - cough

REFERENCE :: WADTAA Wright Air Development Center, Technical Report, U.S. Air Force. (Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: 55-250,10,1955

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 12 ppm/6H/30D-I

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified

REFERENCE :: WADTAA Wright Air Development Center, Technical Report, U.S. Air Force. (Wright-Patterson Air Force Base, OH 45433) Volume(issue)/page/year: 55-250,10,1955

Symbol	GHS02, GHS05, GHS06
Signal Word	Danger
Hazard Statements	H226-H302-H311-H314
Precautionary Statements	P280-P305 + P351 + P338-P310
Personal Protective Equipment	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	T:Toxic;
Risk Phrases	R10;R22;R24;R34
Safety Phrases	S16-S26-S36/37/39-S45-S24/25
RIDADR	UN 2734 8/PG 2
WGK Germany	2
RTECS	TX8400000
Packaging Group	III
Hazard Class	3
HS Code	2921290000

Precursor 8
CAS#:5350-67-4 2-dimethylamino... CAS#:124-40-3 Dimethylamine CAS#:109-64-8 1,3-Dibromopropane CAS#:42779-37-3 1,3-bis(dimethy...
CAS#:17268-47-2 3-(dimethylamin... CAS#:1611-78-5 N,N,N’,N’-tetra... CAS#:17471-59-9 N,N,N',N'-Tetra... CAS#:50-00-0 Formaldehyde
DownStream 10
CAS#:39515-41-8 fenpropathrin [ANSI] CAS#:3179-80-4 Dimethylaminopr... CAS#:22890-11-5 N-[3-(dimethyla... CAS#:27389-68-0 1,3-Propanediam...
CAS#:62-75-9 N-Nitrosodimeth... CAS#:6972-76-5 1,3-Propanediam... CAS#:13440-12-5 1,3-Bis(trimeth... CAS#:21948-96-9 1,3-Propanediam...
CAS#:7651-02-7 Octadecanamide,... CAS#:45267-19-4 Aldox

HS Code	2921290000
Summary	2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

N,N,N',N'-Tetramethyl-1,3-propanediamine as the catalyst of choice for the Baylis-Hillman reaction of cycloalkenone: rate acceleration by stabilizing the zwitterionic intermediate via the ion-dipole interaction. Lee KY, et al.

Tetrahedron Lett. 45(28) , 5485-5488, (2004)

Synthesis of homodimeric monomethine cyanine dyes as noncovalent nucleic acid labels and their absorption and fluorescence spectral characteristics. Deligeorgiev TG, et al.

Dyes and Pigments 44(2) , 131-136, (2000)

Synthesis, physical properties, and structural characterization of. mu.-carbonato-dichlorobis (N,N,N',N'-Tetramethyl-1,3-propanediamine) dicopper(II), LCuCl(CO3)ClCuL, a diamagnetic initiator for the oxidative coupling of phenols by dioxygen. Churchill MR, et al.

Inorg. Chem. 18(8) , 2296-2300, (1979)

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS ...
Source: 824
Target: N/A
External Id: P53MS837

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898

Name: Adrenergic beta2 receptor (ADRB2) small molecule agonists, cell-based qHTS assay
Source: 824
External Id: ADRB2293

Name: Adrenergic beta2 receptor (ADRB2) small molecule antagonists, cell-based qHTS assay
Source: 824
External Id: ADRB2713

Total 193, Current Page 1 of 20

bis[(dimethylamino)methyl]methane

N,N,N′,N′-Tetramethyl-1,3-propanediamine

N,N,N',N'-Tetramethylpropane-1,3-diamine

N1,N1,N3,N3-Tetramethylpropane-1,3-diamine

Tetramethyl-1,3-diaminopropane

MFCD00008337

1,3-Bis(dimethylamino)propane

N,N,N',N'-Tetramethyltrimethylenediamine

N,N,N‘,N‘-Tetramethyl-1,3-propanediamine

TMPDA

N,N,N',N'-Tetramethyl-1,3-propanediamine

N,N,N',N'-TetraMethyl-1,3-diaMinopropane

EINECS 203-818-8

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: TMPDA
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Tetramethyl-1,3-diaminopropane
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: TMPDA
Price: ￥358.0/500ml ￥108.0/100ml
Purity: 99.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

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TMPDA

Names

Chemical & Physical Properties

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Articles4

TMPDABioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.