N-Nitrosodimethylamine
Modify Date: 2025-08-20 17:41:47
N-Nitrosodimethylamine structure
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Common Name | N-Nitrosodimethylamine | ||
|---|---|---|---|---|
| CAS Number | 62-75-9 | Molecular Weight | 74.082 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 152.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C2H6N2O | Melting Point | 50ºC | |
| MSDS | Chinese USA | Flash Point | 36.1±18.7 °C | |
| Symbol |
GHS02, GHS06, GHS08 |
Signal Word | Danger | |
Use of N-NitrosodimethylamineDimethylnitrosamine (NDMA) is a potent hepatotoxin, carcinogen and mutagen. Dimethylnitrosamine can be used to induces liver tumors[1][2]. |
| Name | N,N-dimethylnitrous amide |
|---|---|
| Synonym | More Synonyms |
| Description | Dimethylnitrosamine (NDMA) is a potent hepatotoxin, carcinogen and mutagen. Dimethylnitrosamine can be used to induces liver tumors[1][2]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 152.0±0.0 °C at 760 mmHg |
| Melting Point | 50ºC |
| Molecular Formula | C2H6N2O |
| Molecular Weight | 74.082 |
| Flash Point | 36.1±18.7 °C |
| Exact Mass | 74.048012 |
| PSA | 32.67000 |
| LogP | -0.64 |
| Vapour Pressure | 4.6±0.2 mmHg at 25°C |
| Index of Refraction | 1.427 |
| InChIKey | UMFJAHHVKNCGLG-UHFFFAOYSA-N |
| SMILES | CN(C)N=O |
| Stability | Stability Stable, but light-sensitive. Combustible. Incompatible with strong oxidizing agents, strong bases, strong reducing agents. |
| Symbol |
GHS02, GHS06, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H301 + H311 + H331-H350-H370 |
| Precautionary Statements | P201-P210-P260-P280-P301 + P310-P311 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | T+,N,T,F |
| Risk Phrases | 45-25-26-48/25-51/53-39/23/24/25-23/24/25-11 |
| Safety Phrases | S53-S45-S61-S36/37 |
| RIDADR | UN 3382 6.1/PG 1 |
| WGK Germany | 3 |
| RTECS | IQ0525000 |
| Packaging Group | III |
| Hazard Class | 6.1(b) |
| Precursor 8 | |
|---|---|
| DownStream 10 | |
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[Effect of cordyceps polysaccharide on lipid peroxidation of rats with dimethylnitrosamine-induced liver fibrosis].
Zhongguo Zhong Yao Za Zhi 38(3) , 391-6, (2013) To observe the pharmacological effect of Cordyceps polysaccharide on dimethylnitrosamine (DMN)-induced liver fibrosis in rats.DMN rat liver fibrosis model was established and divided into the normal g... |
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Relationship between organic precursors and N-nitrosodimethylamine (NDMA) formation in tropical water sources.
J. Water Health 12(4) , 736-46, (2014) The presence of organic compounds in water sources is one of the concerns in water treatment. They are potential precursors of disinfection byproducts (DBPs) and thus induce health problems in humans.... |
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Developing structure-activity relationships for the prediction of hepatotoxicity.
Chem. Res. Toxicol. 23 , 1215-22, (2010) Drug-induced liver injury is a major issue of concern and has led to the withdrawal of a significant number of marketed drugs. An understanding of structure-activity relationships (SARs) of chemicals ... |
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Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273
|
|
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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|
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
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Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600
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Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958
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Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482
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Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233
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| N-NITROSODIMETHYLAMINE |
| dimethyl-nitrosoamine |
| EINECS 200-549-8 |
| N-Methyl-N-nitrosomethanamine |
| MFCD00002053 |
| Methanamine,N-methyl-N-nitroso |
| Dimethylnitrosamine |
| Nitrosodimethylamine |
| DMNA |
| [14C]-Dimethylnitrosamine |
| N,N-Dimethylnitrosamine |