taxamairin B

Modify Date: 2024-01-17 10:49:13

taxamairin B Structure
taxamairin B structure
Common Name taxamairin B
CAS Number 110300-77-1 Molecular Weight 352.42400
Density 1.17g/cm3 Boiling Point 577.4ºC at 760mmHg
Molecular Formula C22H24O4 Melting Point N/A
MSDS N/A Flash Point 252.7ºC

 Use of taxamairin B


Taxamairin B is a potent anti-inflammatory agent. Taxamairin B decreases proinflammatory cytokines (TNF-α, IL-1β and IL-6) expression and the production of NO and ROS in LPS-induced RAW264.7 cells. Taxamairin B exhibits significantprotective effects in LPS-induced acute lung injury in mice[1][2].

 Names

Name 1,2-dimethoxy-7,7-dimethyl-3-propan-2-yldibenzo[2,4-d:4',5'-e][7]annulene-5,8-dione
Synonym More Synonyms

 taxamairin B Biological Activity

Description Taxamairin B is a potent anti-inflammatory agent. Taxamairin B decreases proinflammatory cytokines (TNF-α, IL-1β and IL-6) expression and the production of NO and ROS in LPS-induced RAW264.7 cells. Taxamairin B exhibits significantprotective effects in LPS-induced acute lung injury in mice[1][2].
Related Catalog
References

[1]. Liu M, et al. Rapid access to icetexane diterpenes: Their protective effects against lipopolysaccharides-induced acute lung injury via PI3K/AKT/NF-κB axis in macrophages. Eur J Med Chem. 2023 Nov 15;260:115769.  

[2]. Liang JY, et al. Two new antineoplastic diterpenes from Taxus mairei. Chem Pharm Bull (Tokyo). 1987 Jun;35(6):2613-4.  

 Chemical & Physical Properties

Density 1.17g/cm3
Boiling Point 577.4ºC at 760mmHg
Molecular Formula C22H24O4
Molecular Weight 352.42400
Flash Point 252.7ºC
Exact Mass 352.16700
PSA 52.60000
LogP 4.21410
Vapour Pressure 2.48E-13mmHg at 25°C
Index of Refraction 1.581

 Safety Information

HS Code 2914509090

 Customs

HS Code 2914509090
Summary HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Synonyms

Taxamairin B
1H-Dibenzo(a,d)cycloheptene-2,10-dione,6,7-dimethoxy-1,1-dimethyl-8-(1-methylethyl)