Squalane

Modify Date: 2026-07-01 17:48:07

Squalane structure	Common Name	Squalane
	CAS Number	111-01-3	Molecular Weight	422.813
	Density	0.8±0.1 g/cm3	Boiling Point	470.3±0.0 °C at 760 mmHg
	Molecular Formula	C₃₀H₆₂	Melting Point	−38 °C(lit.)
	MSDS	Chinese USA	Flash Point	217.8±0.0 °C

Use of Squalane

Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[1].

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name	2,6,10,15,19,23-hexamethyltetracosane
Synonym	More Synonyms

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description	Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Squalane exhibits a huge potential in nutraceutical and pharmaceutical industries. Squalane shows anticancer, antioxidant, drug carrier, detoxifier, skin hydrating, and emollient activities have been reported both in animal models and in vitro environments[1].
References	[1]. Kim SK, et al. Biological importance and applications of squalene and squalane. Adv Food Nutr Res. 2012;65:223-33.

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Density	0.8±0.1 g/cm3
Boiling Point	470.3±0.0 °C at 760 mmHg
Melting Point	−38 °C(lit.)
Molecular Formula	C₃₀H₆₂
Molecular Weight	422.813
Flash Point	217.8±0.0 °C
Exact Mass	422.485138
LogP	15.59
Vapour Pressure	0.0±0.5 mmHg at 25°C
Index of Refraction	1.448
InChIKey	PRAKJMSDJKAYCZ-UHFFFAOYSA-N
SMILES	CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.

This table provides MSDS information including hazard classification, first‑aid, fire‑fighting, spill handling, operation and storage instructions.

Squalane MSDS(Chinese)

This table summarizes toxicological test data, acute & chronic toxicity and ecological hazard parameters for this chemical.

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XB6070000

CHEMICAL NAME :: Tetracosane, 2,6,10,15,19,23-hexamethyl-

CAS REGISTRY NUMBER :: 111-01-3

BEILSTEIN REFERENCE NO. :: 0776019

LAST UPDATED :: 199709

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C30-H62

MOLECULAR WEIGHT :: 422.92

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - guinea pig

REFERENCE :: CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84063 No. of Facilities: 109 (estimated) No. of Industries: 3 No. of Occupations: 10 No. of Employees: 20918 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84063 No. of Facilities: 1980 (estimated) No. of Industries: 11 No. of Occupations: 32 No. of Employees: 149812 (estimated) No. of Female Employees: 126648 (estimated)

This table covers safety warnings, protective measures, incompatible substances and disposal guidelines for this compound.

Personal Protective Equipment	Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	XB6070000
HS Code	2901100000

This table presents publicly reported synthetic routes, reaction conditions, reactants and product information of the compound.

This table lists upstream starting materials and downstream derivative products related to this chemical.

Precursor 10
CAS#:18794-84-8 (E)-β-Farnesene CAS#:111-02-4 Squalene CAS#:51627-57-7 6-azido-tetrazo... CAS#:78791-60-3 2,6,10,15,19,23...
CAS#:19317-11-4 FARNESAL CAS#:13786-84-0 3,7,11-trimethy... CAS#:78791-59-0 ((7,11-dimethyl... CAS#:3796-70-1 Geranylacetone
CAS#:59905-15-6 3-hydroxy-3,7,1... CAS#:106-28-5 (2E,6E)-Farnesol
DownStream 2
CAS#:2216-33-3 3-Methyloctane CAS#:79054-29-8 squalane cation

This table shows customs‑related data including HS‑code, tariff and regulatory conditions for import and export.

HS Code	2901100000
Summary	2901100000 saturated acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

This table lists relevant public references with title, journal and publication metadata for this compound.

Biological importance and applications of squalene and squalane.

Adv. Food Nutr. Res. 65 , 223-33, (2012)

Squalene is a polyunsaturated hydrocarbon with a formula of C₃₀H₅₀. Squalene can be found in certain fish oils, especially shark liver oil, in high amounts and some vegetable oils in relatively smalle...

How membrane permeation is affected by donor delivery solvent.

Phys. Chem. Chem. Phys. 14(44) , 15525-38, (2012)

We investigate theoretically and experimentally how the rate and extent of membrane permeation is affected by switching the donor delivery solvent from water to squalane for different permeants and me...

Effects of squalene/squalane on dopamine levels, antioxidant enzyme activity, and fatty acid composition in the striatum of Parkinson's disease mouse model.

J. Oleo Sci. 62(1) , 21-8, (2013)

Active oxygen has been implicated in the pathogenesis of Parkinson's disease (PD); therefore, antioxidants have attracted attention as a potential way to prevent this disease. Squalene, a natural trit...

This table contains target information, in‑vitro & in‑vivo assay data for this compound.

Name: Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
Source: NCGC
External Id: SNCA-p-activity-luciferase

Name: Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
Source: 824
External Id: CYP273

Name: p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
Source: 824
Target: N/A
External Id: P53600

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: qHTS ce...
Source: 824
Target: N/A
External Id: P53MS958

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes: Summary
Source: 824
External Id: P53MS482

Name: p53 small molecule agonists, cell-based qHTS assay
Source: 824
External Id: P53344

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS233

Name: p53 small molecule agonists, cell-based qHTS assay with human liver microsomes: qHTS ...
Source: 824
Target: N/A
External Id: P53MS837

Name: p53 small molecule agonists, cell-based qHTS assay with rat liver microsomes
Source: 824
Target: tumor suppressor p53 [Homo sapiens]
External Id: P53MS898

Name: Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve...
Source: NCGC
Target: N/A
External Id: OBG420

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This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

Squalane

Robane

Cosbiol

Perhydrosqualene

2,6,10,15,19,23-hexamethylteracosane

Spinacane

2,6,10,15,19,23-Hexamethyltetracosane

Dodecahydrosqualene

2,6,10,15,19,23-Hexamethyltetracosane,Cosbiol,Perhydrosqualene

Vitabiosol

MFCD00008953

Hexamethyltetracosane

EINECS 203-825-6

poly(ethylenepropylene)

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What are the uses of 2,6,10,15,19,23-hexamethyltetracosane?

A: Main uses of 2,6,10,15,19,23-hexamethyltetracosane: Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[1].

Q: What is the SMILES notation of 2,6,10,15,19,23-hexamethyltetracosane?

A: SMILES notation of 2,6,10,15,19,23-hexamethyltetracosane is CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C.

Q: What English synonyms does 2,6,10,15,19,23-hexamethyltetracosane have?

A: English synonyms of 2,6,10,15,19,23-hexamethyltetracosane: Squalane, Robane, Cosbiol, Perhydrosqualene, 2,6,10,15,19,23-hexamethylteracosane, Spinacane, 2,6,10,15,19,23-Hexamethyltetracosane, Dodecahydrosqualene, 2,6,10,15,19,23-Hexamethyltetracosane,Cosbiol,Perhydrosqualene, Vitabiosol, MFCD00008953, Hexamethyltetracosane, EINECS 203-825-6, poly(ethylenepropylene).

Q: What is the melting point of 2,6,10,15,19,23-hexamethyltetracosane?

A: Melting point of 2,6,10,15,19,23-hexamethyltetracosane is −38 °C(lit.).

Q: What is the molecular weight of 2,6,10,15,19,23-hexamethyltetracosane?

A: Molecular weight of 2,6,10,15,19,23-hexamethyltetracosane is 422.813.

Q: What are the downstream products of 2,6,10,15,19,23-hexamethyltetracosane?

A: Related downstream products(CAS) of 2,6,10,15,19,23-hexamethyltetracosane: 2216-33-3;79054-29-8.

Q: What is the boiling point of 2,6,10,15,19,23-hexamethyltetracosane?

A: Boiling point of 2,6,10,15,19,23-hexamethyltetracosane is 470.3±0.0 °C at 760 mmHg.

Q: What is the safety information for 2,6,10,15,19,23-hexamethyltetracosane?

A: Safety information for 2,6,10,15,19,23-hexamethyltetracosane: S26-S36.

Q: What is the molecular formula of 2,6,10,15,19,23-hexamethyltetracosane?

A: Molecular formula of 2,6,10,15,19,23-hexamethyltetracosane is C30H62.

Q: What are the upstream materials of 2,6,10,15,19,23-hexamethyltetracosane?

A: Related upstream materials(CAS) of 2,6,10,15,19,23-hexamethyltetracosane: 18794-84-8;111-02-4;51627-57-7;78791-60-3;19317-11-4;13786-84-0;78791-59-0;3796-70-1;59905-15-6;106-28-5.

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd

Dayang Chem (Hangzhou) Co., Ltd.

Henan Tianfu Chemical Co., Ltd.

Zhongshan Xingrui Chemical Co. , Ltd.

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Squalane
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Squalane
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: Squalane
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

Zhongshan Xingrui Chemical Co. , Ltd.
China
Product Name: Squalane
Price: ￥Inquiry/25kg
Purity: 99.0%
Delivery: Inquiry
Contact: Wang Jie
Email: 3096638339@qq.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.